Utility of Lung Clearance Index Testing as a Noninvasive Marker of Deployment-related Lung Disease.

Objective: The aim of this study was to determine utility and sensitivity of lung clearance index (LCI) testing as a marker of lung injury in symptomatic military deployers compared with healthy controls.

Methods: We tested 24 healthy controls and 28 deployers with respiratory symptoms (17 of 28 with definite and 11 of 28 with probable deployment-related lung disease). We compared mean LCI scores between deployers and controls using t tests; adjusted tests were derived from multiple regression models.