Amniotic fluid peptides predict postnatal kidney survival in developmental kidney disease.

Although a rare disease, bilateral congenital anomalies of the kidney and urinary tract (CAKUT) are the leading cause of end stage kidney disease in children. Ultrasound-based prenatal prediction of postnatal kidney survival in CAKUT pregnancies is far from accurate. To improve prediction, we conducted a prospective multicenter peptidome analysis of amniotic fluid spanning 140 evaluable fetuses with CAKUT.

Ultrasound features of fetal toxoplasmosis: A contemporary multicenter survey in 88 fetuses.

Objective: To describe the lesions detected by prenatal ultrasound examination in congenital toxoplasmosis (CT).

Methods: We retrospectively analyzed all cases of fetal infection with Toxoplasma gondii with ultrasound anomalies described by fetal medicine experts in 2009 to 2019 in 30 French centers.

Results: Eighty-eight cases of CT were included.

C5orf42 is the major gene responsible for OFD syndrome type VI.

Oral-facial-digital syndrome type VI (OFD VI) is a recessive ciliopathy defined by two diagnostic criteria: molar tooth sign (MTS) and one or more of the following: (1) tongue hamartoma (s) and/or additional frenula and/or upper lip notch; (2) mesoaxial polydactyly of one or more hands or feet; (3) hypothalamic hamartoma. Because of the MTS, OFD VI belongs to the "Joubert syndrome related disorders". Its genetic aetiology remains largely unknown although mutations in the TMEM216 gene, responsible for Joubert (JBS2) and Meckel-Gruber (MKS2) syndromes, have been reported in two OFD VI patients.

Attachment states of mind in late adolescence and the quality and course of romantic relationships in adulthood.

The purpose of this study was to examine the longitudinal relations between attachment state of mind in late adolescence and romantic relationships in adulthood. Participants were drawn from two independent studies that were conducted respectively in 1992 and 1996 and that involved the administration of the Adult Attachment Interview (AAI) to 167 college students. They were followed-up in 2007 (N = 99) to investigate different aspects of their romantic relationships since college.

Eyebrow position recognition and correction in reconstructive and cosmetic surgery.

Objectives: To improve (1) recognition of eyebrow ptosis, asymmetry, or deformity and (2) selection of the appropriate surgical technique based on the patient's underlying etiology.

Design: Nonrandomized, retrospective study of patients undergoing surgical correction of eyebrow asymmetry. Forty consecutive patients were identified as having asymmetric eyebrow ptosis or deformity.