Global Presence and Penetrance of -Related Disorder.

Objectives: To highlight the worldwide presence of -related disorder (-RD), discuss its penetrance, and provide the first haplotype analysis.

Methods: Data on patients worldwide were collected, including demographics, genotype, family history, and clinical status. For haplotype analysis, polymorphisms of short tandem repeats in 3 distinct families with p.

A Digital Health Intervention to Lower Cardiovascular Risk: A Randomized Clinical Trial.

Importance: South Asian individuals have a high burden of premature myocardial infarction (MI).

Objectives: To test whether a digital health intervention (DHI) designed to change diet and physical activity improves MI risk among a South Asian population.

Design, Setting, And Participants: This single-blind, community-based, randomized clinical trial with 1-year follow-up was performed among South Asian men and women 30 years or older and living in Ontario and British Columbia who were free of cardiovascular disease.

South Asian Heart Risk Assessment (SAHARA): Randomized Controlled Trial Design and Pilot Study.

Background: People of South Asian origin suffer a high burden of premature myocardial infarction (MI). South Asians form a growing proportion of the Canadian population and preventive strategies to mitigate the risk of MI in this group are needed. Prior studies have shown that multimedia interventions are effective and feasible in inducing health behavior changes among the obese, smokers, and among those who are sedentary.