Surrogate obesity negatively impacts pregnancy rates in third-party reproduction.

In a retrospective cohort review of third-party reproduction, we observed that surrogate body mass index (BMI) negatively impacts implantation rates in oocyte-donor in vitro fertilization cycles. A BMI > or =35 kg/m(2) cutoff is associated with a statistically significant decrease in pregnancy rates but not miscarriage rates.

Accuracy of FISH analysis in predicting chromosomal status in patients undergoing preimplantation genetic diagnosis.

Objective: The purpose of this study was to determine the positive predictive value (PPV) and negative predictive value (NPV) of FISH analysis and to determine which chromosomal abnormalities are most frequently confirmed.

Design: Prospective observational.

Setting: IVF laboratory.

Rescue intracytoplasmic sperm injection and preimplantation genetic diagnosis in combination can result in pregnancy.

Objective: To report the birth of a baby from the transfer of one embryo after rescue intracytoplasmic sperm injection (ICSI) and preimplantation genetic diagnosis (PGD).

Design: Case report.

Setting: IVF center.

Degree of facial and body terminal hair growth in unselected black and white women: toward a populational definition of hirsutism.

Context: Hirsutism (i.e. facial and body terminal hair growth in a male-like pattern in women) is the principal clinical sign of hyperandrogenism, although its definition remains unclear.

Fluorescence in situ hybridization reanalysis of day-6 human blastocysts diagnosed with aneuploidy on day 3.

Objective: To determine the concordance of day-6 blastocyst analysis with the day-3 fluorescence in situ hybridization (FISH) aneuploidy diagnosis.

Design: Retrospective study.

Setting: In vitro fertilization laboratory.

Three dimensional/four dimensional ultrasound-guided embryo transfer using the maximal implantation potential point.

Objective: To evaluate the use of maximal implantation potential (MIP) point in conjunction with a 3D/4D ultrasound in order to facilitate embryo transfers and potentially improve pregnancy rate.

Design: Retrospective, observational study.

Setting: IVF Center.

Prevalence of insulin resistance in the polycystic ovary syndrome using the homeostasis model assessment.

Objective: To determine the prevalence of insulin resistance (IR) in a large population of patients with the polycystic ovary syndrome (PCOS).

Design: Prospective, case-control.

Setting: University medical center.