Improving the Quality of EDTA-treated Blood Specimens from Mice.

Nonterminal blood sampling in laboratory mice is a very common procedure. With the goal of improving animal welfare, different sampling sites and methods have been compared but have not achieved a consensus. Moreover, most of these studies overlooked the quality of blood specimens collected.

Reference Values for Hematology, Plasma Biochemistry, Bone Marrow Cytology and Bone Histology of NOD SzJ Immunodeficient Mice.

Highly immunodeficient NSG mice (NOD.SzJ) are commonly used as a models in preclinical studies for patient-derived engraftment. However, despite the frequency of their use, reference values for their clinical pathology markers have not been determined.

Within-day and between-day variability of blood pressure measurement in healthy conscious Beagle dogs using a new oscillometric device.

Objectives: The main objective of this study was to determine the within- and between-day variability of blood pressure measurement in dogs using an oscillometric device, pet-MAP.

Animals, Materials And Methods: Five healthy conscious adult Beagle dogs were used. The dogs were presented in a random order for examinations and the investigators were blinded to the dogs.