Publications by authors named "Catherine Gonthier"
Article Synopsis
- - The study compared trauma care systems in the English NHS and Quebec, Canada, focusing on patient admissions with major trauma from 2014 to 2017 to identify differences in care structures and outcomes.
- - Key findings showed that the NHS had a more advanced prehospital care system and longer hospital stays for certain injuries, while Quebec had quicker transport times for direct cases but longer emergency department stays.
- - Mortality rates varied with injury type, showing higher death rates in Quebec for head injuries but better outcomes for thoracoabdominal injuries, indicating the need for future research to explore quality improvements in trauma care.
Objectives: To develop a hospital indicator of resource use for injury admissions.
Methods: We focused on resource use for acute injury care and therefore adopted a hospital perspective. We included patients ≥16 years old with an Injury Severity Score >9 admitted to any of the 57 trauma centers of an inclusive Canadian trauma system from 2014 to 2018.
Background: Guidelines for injury care are increasingly moving away from surgical management towards less invasive procedures but there is a knowledge gap on how these recommendations are influencing practice. We aimed to assess inter-hospital variation in surgical intensity for injury admissions and evaluate the correlation between hospital surgical intensity and mortality/complications.
Methods: We included adults admitted for major trauma between 2006 and 2016 in a Canadian provincial trauma system.
Addressing the concerns of end-of-life patients or their relatives about their family history of cancer could benefit patients and family members. Little is known about how palliative care providers respond to these concerns. The purpose of this pilot study was to assess palliative care providers' knowledge about familial and hereditary cancers and explore their exposure to patients' and relatives' concerns about their family history of cancer, and their self-perceived ability to deal with such concerns.
View Article and Find Full Text PDFProvision of a molecularly confirmed diagnosis in a timely manner for children and adults with rare genetic diseases shortens their "diagnostic odyssey," improves disease management, and fosters genetic counseling with respect to recurrence risks while assuring reproductive choices. In a general clinical genetics setting, the current diagnostic rate is approximately 50%, but for those who do not receive a molecular diagnosis after the initial genetics evaluation, that rate is much lower. Diagnostic success for these more challenging affected individuals depends to a large extent on progress in the discovery of genes associated with, and mechanisms underlying, rare diseases.
View Article and Find Full Text PDFObjective: To estimate the extent of changes in mean BLLs from colder to warmer months, in children aged 1-5 years with different status of lead in colder months.
Methodology: We performed a systematic review using an in-house algorithm developed in MEDLINE, EMBASE, Web of Science, and CINHAL. Search was performed between November 2012 and July 2013, and data evaluation and extraction were subsequently conducted.
To improve our understanding of the organization and evolution of the wheat (Triticum aestivum) genome, we sequenced and annotated 13-Mb contigs (18.2 Mb) originating from different regions of its largest chromosome, 3B (1 Gb), and produced a 2x chromosome survey by shotgun Illumina/Solexa sequencing. All regions carried genes irrespective of their chromosomal location.
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