Screening of SLC26A4, FOXI1 and KCNJ10 genes in unilateral hearing impairment with ipsilateral enlarged vestibular aqueduct.

Objective: To investigate the implication of SLC26A4, FOXI and KCNJ10 genes in unilateral hearing impairment associated with ipsilateral inner ear malformation (Enlargement of the vestibular aqueduct and/or Mondini dysplasia).

Methods: We have gathered 25 patients presenting unilateral hearing impairment and ipsilateral enlarged vestibular aqueduct. For each of the patients, we have analyzed SLC26A4, FOXI1 and KCNJ10 genes sequences.

[Epidemiology of seasonal spring-time allergic rhinitis in adults in France].

Objective: Describe the profile of patients consulting a general practitioner or allergologist for seasonal spring-time allergic rhinitis (SAR) in France.

Methods: 3.348 physicians (3.

Diffuse nasal polyposis and endonasal endoscopic surgery: long-term results, a 65-case study.

Objective: To analyze the efficacy of a standardized surgical procedure in patients with nasal polyposis.

Study Design: Prospective study of nonrandomized cases from a single institution.

Methods: An inception cohort of 65 consecutive patients with nasal polyposis observed from January 1994 to December 1997.

Retrospective case study of carbon dioxide laser stapedotomy with lens-based and mirror-based micromanipulators.

Most clinical studies on carbon dioxide (CO2) (lambda = 10.6 mm) laser stapedotomy have been carried out with the laser guided by a conventional lens-based micromanipulator, with the attendant risks of correct aiming (HeNe) and surgical (CO2) beam misalignment. Hence, engineering advances have attempted to improve laser targeting as well as the spot size focus.