Publications by authors named "Catherine F M Bowden"
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Synopsis of recent research by authors named "Catherine F M Bowden"
- Catherine F M Bowden's research primarily focuses on the structural and functional analysis of the IsdB receptor from Staphylococcus aureus, which plays a critical role in the extraction of heme from human hemoglobin to support bacterial growth and virulence during infections.
- Her work has highlighted the importance of IsdB in bacterial iron acquisition, detailing its mechanism of quickly binding and extracting heme, and the subsequent transfer of heme to another protein, IsdA, within the bacterial system.
- Bowden's findings underscore the significance of IsdB in enhancing our understanding of bacterial pathogenesis and could inform potential therapeutic strategies targeting iron acquisition in bacterial infections.