Publications by authors named "Catherine E Pringle"
Background: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) refractory to conventional therapy can lead to marked disability and represents a therapeutic challenge.
Objective: To report five cases of treatment-refractory disabling CIDP treated with autologous hematopoietic stem cell transplantation (AHSCT).
Methods: This was a retrospective cohort study from a tertiary care referral center for both neuromuscular disease and AHSCT.
Article Synopsis
- Spinal muscular atrophy (SMA) is primarily caused by issues with the SMN1 gene on chromosome 5q13, with Type III being a milder childhood variant that can allow for a normal life expectancy despite some motor difficulties.
- A case study details a 55-year-old woman who faced motor challenges from age two and experienced unexpected sensory issues in her mid-thirties, with her symptoms never clearly diagnosed during her lifetime.
- Autopsy results revealed classic signs of motor neuron degeneration and significant hemosiderin deposits in her spinal cord, providing insight into her sensory symptoms and linking them to both spinal cord abnormalities and the concept of duropathy.