Comparative study of hematological responses to platinum group metals, antimony and silver nanoparticles in animal models.

Research was conducted to examine the hematological effects of heavy metals (platinum (Pt ((IV))), palladium (Pd ((II))), rhodium (Rh ((III))), antimony (Sb ((III)) and Sb ((V))), and silver nanoparticles (AgNPs)) on white blood cells in mammalian (rat) and avian (chick embryo) models. These metals are used in many everyday products and are accumulating in our environment. Six-week old Sprague-Dawley female rats were treated daily by gavage and six-day old, fertile, specific pathogen-free white leghorn strain chick embryos' eggs were injected on days 7 and 14 of incubation with 0.

Heparin-Induced thrombocytopenia (HIT): a case study.

Heparin-induced thrombocytopenia (HiT) ranges from an asymptomatic reaction to heparin with a transient mild thrombocytopenia (HIT I) to a life- and limb-threatening immunological reaction, heparin-induced thrombocytopenia with thrombosis (HITT or HIT II). HITT can occur in patients with any heparin exposure and must be recognized and and symptomatic and/or fatal thrombosis. HIT will be discussed using a case study approach.