Innexins Ogre and Inx2 are required in glial cells for normal postembryonic development of the Drosophila central nervous system.

Innexins are one of two gene families that have evolved to permit neighbouring cells in multicellular systems to communicate directly. Innexins are found in prechordates and persist in small numbers in chordates as divergent sequences termed pannexins. Connexins are functionally analogous proteins exclusive to chordates.