Publications by authors named "Catherine E Garrison"
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Synopsis of recent research by authors named "Catherine E Garrison"
- Catherine E Garrison's research focuses on understanding the interactions between toxins and voltage-gated sodium channels, particularly examining how these toxins modulate channel activity and what mechanisms organisms use to resist their effects.
- Significant findings include the uncovering of possible toxin resistance mechanisms in poison birds and frogs, suggesting that it may involve "toxin sponge" proteins rather than sodium channel mutations, as detailed in her study on batrachotoxin.
- Garrison's studies also explore the structure-activity relationships of various toxins, such as beta-pompilidotoxin and veratridine, revealing insight into their effects on human neuronal sodium channels, which could inform therapeutic implications for neurological disorders.
