Publications by authors named "Catherine Crola"
Frailty is a multifaceted condition that affects many older adults and marks decline on areas such as cognition, physical condition, and nutritional status. Frail individuals are at increased risk for the development of disability, dementia, and falls. There are hardly any health services that enable the identification of prefrail individuals and that focus on prevention of further functional decline.
View Article and Find Full Text PDFObjectives. The aim of the study was to assess self-reported medication adherence measure in patients selected during a health education and health promotion focused event held in the Campania region. The study also assessed sociodemographic determinants of adherence.
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- Activation of CaMKII is necessary for signaling pathways that lead to cardiac hypertrophy, and its interaction with ERK may facilitate this process by promoting ERK's movement into the nucleus.
- In experiments with H9C2 cardiomyoblasts, specific inhibitors of CaMKII and ERK reduced their activation and prevented nuclear accumulation, which in turn diminished hypertrophic responses caused by phenylephrine treatment.
- In vivo studies on hypertensive rats showed that treatment with CaMKII inhibitors significantly reduced cardiac size and mass, suggesting that targeting the CaMKII-ERK interaction could be a promising strategy to prevent cardiac hypertrophy.