Publications by authors named "Catherine Chmiel"
Oral supplementation with L-citrulline, which is sequentially converted to L-arginine then nitric oxide, improves vascular biomarkers and reduces blood pressure in non-pregnant, hypertensive human cohorts and pregnant mice with a pre-eclampsia-like syndrome. This early-phase randomised feasibility trial assessed the acceptability of L-citrulline supplementation to pregnant women with chronic hypertension and its effects on maternal BP and other vascular outcomes. Pregnant women with chronic hypertension were randomised at 12-16 weeks to receive 3-g L-citrulline twice daily (n = 24) or placebo (n = 12) for 8 weeks.
View Article and Find Full Text PDFChronic hypertension in pregnancy is associated with significant adverse pregnancy outcomes, increasing the risk of pre-eclampsia, fetal growth restriction and preterm birth. Dietary nitrate, abundant in green leafy vegetables and beetroot, is reduced in vivo to nitrite and subsequently nitric oxide, and has been demonstrated to lower blood pressure, improve vascular compliance and enhance blood flow in non-pregnant humans and animals. The primary aims of this study were to determine the acceptability and efficacy of dietary nitrate supplementation, in the form of beetroot juice, to lower blood pressure in hypertensive pregnant women.
View Article and Find Full Text PDFArticle Synopsis
- Obesity during pregnancy is a big health issue, especially when moms-to-be have a BMI of 30 or higher, which can be risky for both them and their babies.
- Researchers want to test a 10-week program offering healthy lifestyle tips to help these pregnant women improve their health alongside regular doctor check-ups.
- The study will check if the program works by looking at what happens to the women's weight gain, their births, and their overall feelings during pregnancy, using surveys and other tools to collect information.