Effect of regenerative injection therapy on function and pain in patients with knee osteoarthritis: a randomized crossover study.

Objective: We assessed the effectiveness of regenerative injection therapy (RIT) to relieve pain and restore function in patients with knee osteoarthritis.

Design: Crossover study where participants were randomly assigned to receive exercise therapy for 32 weeks in combination with RIT on weeks 0, 4, 8, and 12 or RIT on weeks 20, 24, 28, and 32.

Patients: Thirty-six patients with chronic knee osteoarthritis.