Walking energetics, fatigability, and fatigue in older adults: the study of energy and aging pilot.

Background: Slow gait speed increases morbidity and mortality in older adults. We examined how preferred gait speed is associated with energetic requirements of walking, fatigability, and fatigue.

Methods: Older adults (n = 36, 70-89 years) were categorized as slow or fast walkers based on median 400-m gait speed.

Expanding the pathologic spectrum of light chain deposition disease: a rare variant with clinical follow-up of 7 years.

We report an unusual histologic manifestation of light chain deposition disease in a 69-year-old female patient, who presented with nephrotic syndrome and an increased serum creatinine. The renal biopsy findings by light and electron microscopy suggested a glomerulonephritis with massive immune-complex deposition, such as lupus nephritis. However, the overall clinical scenario was inconsistent with lupus.