Effect of tumor necrosis factor antagonism on allergen-mediated asthmatic airway inflammation.

Objective: To assess whether tumor necrosis factor (TNF) antagonism can attenuate eosinophilic airway inflammation in patients with mild-to-moderate allergic asthma.

Design: Randomized, double-blind, placebo-controlled trial.

Setting: National Institutes of Health (NIH) Clinical Center.