Publications by authors named "Catherine A Cremona"
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Synopsis of recent research by authors named "Catherine A Cremona"
Catherine A Cremona's research primarily focuses on cell signaling pathways, tissue regeneration, and the mechanisms underlying stem cell regulation, with significant findings related to how these processes contribute to cancer development and tissue homeostasis.
In her studies, she introduced the concept of "paligenosis," describing a conserved program for tissue regeneration involving quiescent cell proliferation mediated through autophagy and mTORC1 signaling.
Additionally, Cremona's work highlights the role of post-translational modifications, specifically sumoylation and ubiquitination, in the DNA damage response and cellular decision-making related to differentiation and proliferation in various tissue contexts.