Prospective comparison of three guideline development methods for treatment of actinic keratosis.

Objective: To compare three methods of guideline development, to see whether using alternative evidence-based methods resulted in variation of recommendations for treating actinic keratosis.

Methods: Method 1 followed a standard multiple session evidence-based approach with a working group. In method 2 recommendations were formulated by a working group during a 2-day conference.

Off-label use of azathioprine in dermatology: a systematic review.

Objective: To summarize evidence regarding the effectiveness, efficacy, and safety of off-label azathioprine use in dermatology.

Data Sources: We searched the MEDLINE (1950-2009), EMBASE (1980-2009), and CENTRAL (1996-2009) databases on October 9, 2009. The main search terms were azathioprine and its synonyms.