Publications by authors named "Catharine Dietrich"
Article Synopsis
- Excessive dietary fat intake is linked to higher plasma lipid levels, decreased bone mineral density, and greater fracture risk, particularly in older postmenopausal women.
- This study aimed to explore sex differences in lipid metabolism's effect on bone regeneration using a rib resection model in mice with modified LDL receptors.
- Findings revealed that high-fat diets increased cholesterol and triglyceride levels in Ldlr mice without sex differences, but male Ldlr mice showed reduced bone regeneration shortly after surgery, highlighting temporary negative effects of hyperlipidemia on male bone healing.
Stem cells have emerged as a promising cell source to heal, replace or regenerate tissue and organs damaged by aging, injury or diseases. The intestinal epithelium is the most rapidly renewing tissue in our body, which is maintained by intestinal stem cells (ISCs), located at the bottom of the crypts. ISCs continuously replace lost or injured intestinal epithelial cells in organisms ranging from Drosophila to humans.
View Article and Find Full Text PDFAging is the continuous loss of tissue and organ function over time. MicroRNAs (miRNAs) are thought to play a vital role in this process. miRNAs are endogenous small noncoding RNAs that control the expression of target mRNA.
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