Publications by authors named "Catharina Gilde"
Article Synopsis
- * It analyzed data from 578 treatment-naïve melanoma patients receiving anti-PD-1 therapy, distinguishing between those who took antibiotics before or during treatment.
- * Results indicate that antibiotic use within 60 days before starting ICB is linked to poorer progression-free survival (PFS) and overall survival (OS), while antibiotics taken after treatment initiation do not significantly impact these outcomes.
Background: The impact of immunosuppressive therapy (IST) on immune-checkpoint inhibition (ICI) is unclear.
Methods: Patients with unresectable advanced melanoma (MM) treated with ICI in the years 2011-2020 were identified from the prospective multicenter German skin cancer registry ADOREG. Patients with IST within 60 days before, or within 30 days after start of ICI were compared to patients without IST.