Computerized analysis of the fetal heart rate in pregnancies complicated by preterm premature rupture of membranes (pPROM).

Objective: We aimed to show that in pregnancies complicated by preterm premature rupture of membranes (pPROM), there are alterations to the fetal heart rate pattern that can be detected by computerized analysis.

Methods: The study population consisted of 27 pregnant women with pPROM at 29-34 weeks of gestation and 33 normal pregnancies matched according to age, parity and gestation. A 30-minute fetal heart rate (FHR) tracing was analyzed by computer and umbilical artery cord blood was collected at birth.

Transabdominal amnioinfusion in preterm premature rupture of membranes: a randomised controlled trial.

Objective: To evaluate the role of transabdominal amnioinfusion in improving the perinatal outcomes of pregnancies complicated by preterm premature rupture of membranes (pPROM).

Design: A randomised controlled trial.

Setting: A teaching hospital in Italy, obstetric unit.

Amniotic levels of nitric oxide and vascular endothelial growth factor in pregnancy with subsequent intrauterine fetal death.

Objective: Nitric oxide (NO) and vascular endothelial growth factor (VEGF) regulate angiogenesis and seem involved in the early stages of placentation. If angiogenesis is reduced, this may lead to poor placentation and fetal death. This study was aimed to determine whether VEGF and NO are associated to subsequent fetal death.

Amniotic vascular endothelial growth factor (VEGF) and nitric oxide (NO) in women with subsequent preeclampsia.

Objective: To assess whether amniotic fluid concentrations of nitric oxide (NO) and vascular endothelial growth factor (VEGF) in early pregnancy correlate to subsequent preeclampsia.

Study Design: We performed a retrospective study to assess VEGF and NO on the second trimester amniotic fluid of 15 healthy women, and 15 women who subsequently developed preeclampsia.

Results: In women with subsequent preeclampsia, both VEGF (213.