Publications by authors named "Caterina Maietta"
Background: No information is currently available regarding the natural history of asymptomatic intracranial aneurysms in beta-thalassemia, raising several concerns about their proper management.
Methods: We performed a prospective longitudinal three-year-long MR-angiography study on nine beta-thalassemia patients (mean-age 40.3 ± 7.
Objectives: A strikingly increased headache prevalence was recently noted in Sri Lankan beta-thalassemia patients, raising several concerns regarding long-term neurological involvement in this condition.
Methods: We interviewed on headache occurrence and characteristics 102 Italian beta-thalassemia patients and 129 healthy controls. 3T-MRI, MR-angiography, MR-venography, cognitive and psychiatric findings were considered.
Brain functional impairment in beta-thalassaemia: the cognitive profile in Italian neurologically asymptomatic adult patients in comparison to the reported literature.
Br J Haematol
August 2019
Article Synopsis
- A study examined cognitive function in 74 adult patients with beta-thalassaemia and 45 healthy controls, finding that patients had significantly lower Full-Scale Intelligence Quotient (FSIQ) scores compared to controls, even when adjusting for education levels.
- Non-transfusion-dependent patients showed a trend towards better cognitive performance than transfusion-dependent patients, yet both groups had similar cognitive profiles on specific tests.
- The study concluded that adults with beta-thalassaemia exhibit cognitive impairments and higher rates of psychological issues, which could lead to serious long-term socio-economic challenges.