Publications by authors named "Caterina Felici"
Background: Associations of common infections with Alzheimer's disease have been reported, but potential mechanisms underlying these relationships are unclear. A hypothesised mechanism is amyloid-beta (Aβ) aggregation as a defense mechanism in response to infection, with subsequent tau accumulation. However, no studies have assessed associations of infections with cerebral Aβ and tau pathology in vivo.
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- Research-ready data enhances the rigor and opportunities in scientific research by creating a unified data environment, particularly valuable for analyses involving multiple cohorts.
- The C-Surv model was developed through stakeholder feedback and is designed with a structured approach based on 18 relevant data themes, using standard naming conventions for variables in longitudinal studies.
- Implementing this common data model provides significant advantages, as shown by reduced data preparation times compared to specific cohort models, and aids in the efficient discovery and analysis of research data.