Publications by authors named "Caterina Chianella"
Eur J Clin Pharmacol
November 2011
Article Synopsis
- Cholinesterase inhibitors, commonly prescribed for Alzheimer's disease, aim to improve cholinergic neurotransmission, but individual genetic differences may affect treatment outcomes.
- An open study involving 171 Italian AD patients assessed the impact of genetic variations at two loci on the effectiveness of donepezil, galantamine, and rivastigmine over 12 months.
- Results indicated no significant difference in efficacy or tolerability among the treatments, with some patients experiencing cognitive decline after one year.
