[Morris syndrome: clinical contribution].

Authors describe the case of newborn babygirl they observed, presenting a strict vaginal ostium with inguinal testicles, also showed on the echography. The karyotype 46xy allowed to define this case as Morris syndrome.

[Neuropeptides and asthma].

Authors underline the neuropeptides function in the arising of the allergic modulation: the relationship between eNANC-iNANC systems, their mediators and the production of cytokines and immunoglobulins. The above demonstrates that the peptidergic system has a primary role in the complex pathogenetic mechanism of the allergic asthma.

[Antihistaminics in pediatric age].

Histamine determines a variety of physiologic and pathologic responses in different tissues and cells and it is an important chemical mediator on inflammation in allergic disease. Therefore the H1-receptor antagonist are among the most widely used medications in the world. We review here the molecular basis of their action and their clinical pharmacology, efficacy in allergic disorders and adverse reaction with a particular attention in children.

[Erythrohemophagocytic lymphohistiocytosis. A clinical report of 3 cases].

Three infants suffering from hepatosplenomegaly, pancytopenia, hyperlipidemia, low fibrinogen levels and fever are reported. Two patients died during the first year of life, the third one received allogenic bone transplantation and survives. Clinical and haematological features are consistent with diagnosis of hemophagocytic lymphohistiocytosis.

Familial erythrophagocytic lymphohistiocytosis: adverse prognostic significance of delayed diagnosis.

Familial erythrophagocytic lymphohistiocytosis (FEL) is a rare disorder of the monocyte-macrophage system, for which an autosomal recessive mode of inheritance has been postulated. It is characterized by a dismal prognosis and is peculiar of early infancy. Three new cases of infants affected by FEL are reported.

[Elevated atrial natriuretic peptide (ANP) levels and normotension in Bartter's syndrome in childhood].

The authors describe a case of Bartter's syndrome, a variety of disease in the newborn, and they point out the most specific of the disease symptoms, that is the normal PA in presence of elevated plasma renin activity. So it was necessary to determine the ANP, the values of which, controlled for a period of 18 months, appeared above the normal ones. The authors conclude that this date would better explain the apparently contradictory date of the normotension.

[Prevention of acute hypertensive encephalopathy in the course of acute post-streptococcal glomerulonephritis in children: considerations in 31 cases].

The authors analysed 31 cases of an acute hypertensive glomerulonephritis. The antihypertensive efficacy of two medicines: a vasodilator (dihidralazine) and a diuretic (Furosemide) was underlibed an these patients. Their efficacy was evident not only in the stabilization of P.

Treatment of acute idiopathic thrombocytopenic purpura (AITP): cooperative Italian study group results.

A cooperative Italian study group on acute idiopathic thrombocytopenic purpura (AITP) has been designed to evaluate efficacy and safety of no treatment at the onset of the disease and sequential treatment with immunoglobulin and high dose steroid. One hundred thirty-eight patients with AITP entered in the trial. Eleven patients were treated before the end of the waiting period because of bleeding.