Publications by authors named "Catarina Pestana Santos"

Article Synopsis
  • Haemophagocytic lymphohistiocytosis (HLH) can be classified as either primary (P-HLH) or secondary (S-HLH), with S-HLH arising from conditions like infections and autoimmune diseases.
  • Diagnosing HLH is tricky due to its vague symptoms and lack of unique indicators, necessitating awareness and careful consideration of potential triggers for effective treatment.
  • A case study of a young woman with idiopathic S-HLH related to a bacterial infection highlights how prompt diagnosis and antimicrobial therapy can lead to improved outcomes and resolution of symptoms.
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Multiple primary malignancies (MPMs) are defined as two or more histopathologically distinct malignancies in the same individual. MPMs are classified as synchronous when tumors are diagnosed within six months of each other. The most common malignancies in MPMs are melanoma, breast, lung, and prostate cancer.

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Unlabelled: Intraocular lymphoma (IOL) is a rare and life-threatening condition whose aetiology is unclear. Blurred vision, reduced vision, and floaters are common initial symptoms. Posterior vitreous detachment and haemorrhage rarely occur.

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Unlabelled: Graves' disease is an autoimmune disorder that results in hyperthyroidism, caused by autoantibodies to the thyrotropin receptor (TRAbs) stimulating thyroid hormone synthesis, giving rise to a variety of systemic manifestations such as goitre, dermatopathy and orbitopathy. The authors present the case of a 28-year-old man admitted to hospital for a 3-week history of fatigue, shortness of breath, palpitations and diffuse goitre, after recent mild SARS-CoV-2 infection. Laboratory investigation revealed hyperthyroidism with TRAbs elevation.

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Unlabelled: Protein-losing enteropathy (PLGE) is an uncommon condition with a multifactorial origin, that is characterized by excessive loss of serum proteins into the gastrointestinal tract, resulting in hypoproteinaemia and oedema. The authors present the case of a 24-year-old man admitted to hospital for a 2-month history of lower extremity oedema and diarrhoea with a secretory pattern. Blood analysis revealed hypoalbuminaemia and iron deficiency anaemia.

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