Effect of warming anesthetic on pain perception during dental injection: a split-mouth randomized clinical trial.

Background: The purpose of this study is to determine the effectiveness of warming anesthesia on the control of the pain produced during the administration of dental anesthesia injection and to analyze the role of Transient Receptor Potential Vanilloid-1 nociceptor channels in this effect.

Patients And Methods: A double-blind, split-mouth randomized clinical trial was designed. Seventy-two volunteer students (22.