Publications by authors named "Catalina Feistritzer"
Article Synopsis
- - The study investigates how the longest treatment-free interval (TFI) between anti-VEGF injections affects visual acuity and the recurrence of macular edema in patients with branch retinal vein occlusion (BRVO) over five years.
- - It included 60 patients with an average age of nearly 72, finding that 72% experienced recurrence of macular edema, with significant predictors being TFI and initial visual acuity.
- - The results suggest that longer TFIs lead to worse visual outcomes and higher rates of macular edema recurrence, indicating the need for more frequent injections in cases of severe BRVO.
Medial Prefrontal Cortex to Medial Septum Pathway Activation Improves Cognitive Flexibility in Rats.
Int J Neuropsychopharmacol
June 2023
Background: The medial prefrontal cortex (mPFC) is necessary for cognitive flexibility and projects to medial septum (MS). MS activation improves strategy switching, a common measure of cognitive flexibility, likely via its ability to regulate midbrain dopamine (DA) neuron population activity. We hypothesized that the mPFC to MS pathway (mPFC-MS) may be the mechanism by which the MS regulates strategy switching and DA neuron population activity.
View Article and Find Full Text PDFStrategy switching is a form of cognitive flexibility that requires inhibiting a previously successful strategy and switching to a new strategy of a different categorical modality. It is dependent on dopamine (DA) receptor activation and release in ventral striatum and prefrontal cortex, two primary targets of ventral tegmental area (VTA) DA projections. Although the circuitry that underlies strategy switching early in learning has been studied, few studies have examined it after extended discrimination training.
View Article and Find Full Text PDF