Publications by authors named "Catalina Duque-Arango"
Mechanical ventilation (MV) strategies in children on extracorporeal membrane oxygenation (ECMO) have not been studied much and the ventilatory parameters to avoid greater lung damage are still unclear. Our objective was to determine the relationship between conventional tidal volume (4-8 ml/kg, CTV) versus low tidal volume (<4 ml/kg, LTV) and mortality in children with MV at the beginning of ECMO. This was a retrospective cohort study that included 101 (10.
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- An elevated lactate/albumin ratio (LAR) greater than 0.5 in critically ill pediatric patients is linked to higher mortality and microcirculation issues, particularly in children with sepsis.
- In a study involving 178 children admitted to the PICU, those with septic shock showed significantly higher chances of having an elevated LAR and more microvascular blood flow abnormalities.
- The findings suggest that a normal LAR indicates less risk of microcirculatory injury, making LAR a valuable biomarker for assessing sepsis-related complications in pediatric patients.
Time Course of Mechanical Ventilation Driving Pressure Levels in Pediatric Acute Respiratory Distress Syndrome: Outcomes in a Prospective, Multicenter Cohort Study From Colombia, 2018-2022.
Jaime Fernández-Sarmiento Ana María Bejarano-Quintero Jose Daniel Tibaduiza Karen Moreno-Medina Rosalba Pardo Catalina Duque-Arango
Pediatr Crit Care Med
September 2024
Article Synopsis
- High driving pressure (DP) during mechanical ventilation can negatively impact outcomes in pediatric patients with acute respiratory distress syndrome (PARDS), particularly regarding 28-day mortality rates.
- A study of 184 intubated children showed that those with a DP greater than 15 cm H2O at 72 hours had a higher risk for mortality and longer ventilation duration.
- Key findings included that lower tidal volumes were linked to decreased mortality risk, while higher plateau pressures in non-survivors highlighted the importance of managing ventilation parameters effectively.*