Publications by authors named "Catalin Vasile Maftei"

Article Synopsis
  • The study introduces two new alkaloids, 6'-Amino-cinchonine and 6'-Amino-cinchonidine, which feature a primary amino group in their structure, potentially enabling new chemical applications.
  • A method for synthesizing triazole derivatives from these compounds is outlined using the [3 + 2] Huisgen cycloaddition, involving the conversion of amines to azides.
  • The synthesis includes non-substituted and silyl-protected triazoles, with some derivatives analyzed via X-ray diffraction to explore the structural relationship between the quinuclidine ring and the triazole.
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In Southeast Europe, the ethnomedicinal use of Helleborus species has a very long tradition. Cardiac steroids (Hellebrin), cysteine-rich proteins (Hellethionins) and several steroidal saponins have been identified in these plants. Aim of the present work was to investigate the amino acid composition of native extracts from the root and rootstock of Helleborus purpurascens.

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