Publications by Castagliolo I

Publications by authors named "Castagliolo I"

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Deletion of neutral endopeptidase exacerbates intestinal inflammation induced by Clostridium difficile toxin A.

K S Kirkwood N W Bunnett J Maa I Castagliolo B Liu

Am J Physiol Gastrointest Liver Physiol

August 2001

Toxin A (TxA) of Clostridium difficile induces acute inflammation of the intestine initiated by release of substance P (SP) and activation of the neurokinin-1 receptor. However, the mechanisms that terminate this response are unknown. We determined whether the SP-degrading enzyme neutral endopeptidase (NEP, EC 3.

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