We evaluated the ResistancePlus® MG assay in providing macrolide resistance-guided treatment (RGT) for infection at a UK sexual health centre. -positive samples from men with urethritis and women with pelvic inflammatory disease (PID) were tested for macrolide resistance-mediating mutations (MRMMs). MRMM-positive infections were given moxifloxacin 400 mg; otherwise 2 g azithromycin (1 g single dose and then 500 mg OD) was given.
View Article and Find Full Text PDFWe present 2 cases of Mycoplasma genitalium infection that were successfully treated with moxifloxacin despite the presence of quinolone resistance-associated mutations in these strains.
View Article and Find Full Text PDFRecent studies have documented disproportionately high rates of sexually transmitted infections (STIs), HIV, and births among adolescents in rural areas of the United States. Despite this, the majority of sexual health education programs and interventions were developed for adolescents in metropolitan areas, and may not be appropriate or relevant for rural youth. The present study investigates the perspectives of 73 African American youth in rural Georgia who participated in a cognitive-behavioral intervention to reduce sexual risk behaviors, in an effort to understand how the intervention and ones similar to it may be tailored to better meet the needs of rural adolescents.
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