Comparison of Substrate Specificity of -Aminobenzoyl-Glutamate Hydrolase with Carboxypeptidase G.

Reduced folic acid derivatives support biosynthesis of DNA, RNA and amino acids in bacteria as well as in eukaryotes, including humans. While the genes and steps for bacterial folic acid synthesis are known, those associated with folic acid catabolism are not well understood. A folate catabolite found in both humans and bacteria is -aminobenzoyl-glutamate (PABA-GLU).