Lexico-syntactic constraints influence verbal working memory in sentence-like lists.

We test predictions from the language emergent perspective on verbal working memory that lexico-syntactic constraints should support both item and order memory. In natural language, long-term knowledge of lexico-syntactic patterns involving part of speech, verb biases, and noun animacy support language comprehension and production. In three experiments, participants were presented with randomly generated dative-like sentences or lists in which part of speech, verb biases, and animacy of a single word were manipulated.

Are lexical representations graded or discrete?

Most research on mental lexical representations (lemmas) assumes they are discrete and correspond in number to a word's number of distinct meanings. Thus, homophones (), whose meanings are unrelated, have separate lemmas for each meaning (one for , another for ), whereas polysemes (), whose senses are related, have shared lemmas (the same lemma for and ). However, most aspects of cognition are thought to be graded, not discrete; could lemmas be graded too? We conducted a preregistered picture-word interference study with pictures of words whose meanings ranged from unrelated (homophones) to very related (regular polysemes).

A chimpanzee by any other name: The contributions of utterance context and information density on word choice.

An important feature of language production is the flexibility of lexical selection; producers could refer to an animal as chimpanzee, chimp, ape, she, and so on. Thus, a key question for psycholinguistic research is how and why producers make the lexical selections that they do. Information theoretic approaches have argued that producers regulate the uncertainty of the utterance for comprehenders, for example using longer words like chimpanzee if their messages are likely to be misunderstood, and shorter ones like chimp when the message is easy to understand.

A Markov Mixed-Effect Multinomial Logistic Regression Model for Nominal Repeated Measures with an Application to Syntactic Self-Priming Effects.

Syntactic priming effects have been investigated for several decades in psycholinguistics and the cognitive sciences to understand the cognitive mechanisms that support language production and comprehension. The question of whether speakers prime themselves is central to adjudicating between two theories of syntactic priming, activation-based theories and expectation-based theories. However, there is a lack of a statistical model to investigate the two different theories when nominal repeated measures are obtained from multiple participants and items.

Prosody indexes both competence and performance.

Prosody is an important feature of language that conveys a wide range of information. However, prosody is widely considered to be a difficult domain of study within the language sciences. One consequence of this is that existing grammatical theories of prosody fail to explain prosodic choices that seem to arise from nonlinguistic cognitive demands, such as communicative context, top-down expectations, and recent articulatory and acoustic experience.

Downstream Behavioral and Electrophysiological Consequences of Word Prediction on Recognition Memory.

When people process language, they can use context to predict upcoming information, influencing processing and comprehension as seen in both behavioral and neural measures. Although numerous studies have shown immediate facilitative effects of confirmed predictions, the downstream consequences of prediction have been less explored. In the current study, we examined those consequences by probing participants' recognition memory for words after they read sets of sentences.

Self-Priming in Production: Evidence for a Hybrid Model of Syntactic Priming.

Syntactic priming in language production is the increased likelihood of using a recently encountered syntactic structure. In this paper, we examine two theories of why speakers can be primed: error-driven learning accounts (Bock, Dell, Chang, & Onishi, 2007; Chang, Dell, & Bock, 2006) and activation-based accounts (Pickering & Branigan, 1999; Reitter, Keller, & Moore, 2011). Both theories predict that speakers should be primed by the syntactic choices of others, but only activation-based accounts predict that speakers should be able to prime themselves.

Phrase frequency effects in free recall: Evidence for redintegration.

Four experiments examined the effects of word and phrase frequency on free recall. Word frequency did not affect word recall, but when participants studied and recalled lists of compositional adjective-noun phrases (e.g.

Why are repeated words produced with reduced durations? Evidence from inner speech and homophone production.

Acoustic reduction for repeated words could be the result of articulation and motor practice (Lam & Watson, 2014), facilitated production (Kahn & Arnold, 2015; Gahl et al., 2012), or audience design and shared common ground (Galati & Brennan, 2010). We sought to narrow down what kind of facilitation leads to repetition reduction.

"hotdog", not "hot" "dog": The phonological planning of compound words.

Do we say when we say ? In five experiments using the implicit priming paradigm, we assessed whether nominal compounds composed of two free morphemes like or are prepared for production at the segmental level in the same way that two-syllable monomorphemic words (e.g. ) are, or instead as sequences of separable words (e.

The Epstein-Barr virus (EBV)-induced tumor suppressor microRNA MiR-34a is growth promoting in EBV-infected B cells.

Epstein-Barr virus (EBV) infection of primary human B cells drives their indefinite proliferation into lymphoblastoid cell lines (LCLs). B cell immortalization depends on expression of viral latency genes, as well as the regulation of host genes. Given the important role of microRNAs (miRNAs) in regulating fundamental cellular processes, in this study, we assayed changes in host miRNA expression during primary B cell infection by EBV.

Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs.

A role for microRNA (miRNA) has been recognized in nearly every biologic system examined thus far. A complete delineation of their role must be preceded by the identification of all miRNAs present in any system. We elucidated the complete small RNA transcriptome of normal and malignant B cells through deep sequencing of 31 normal and malignant human B-cell samples that comprise the spectrum of B-cell differentiation and common malignant phenotypes.

Patterns of microRNA expression characterize stages of human B-cell differentiation.

Mature B-cell differentiation provides an important mechanism for the acquisition of adaptive immunity. Malignancies derived from mature B cells constitute the majority of leukemias and lymphomas. These malignancies often maintain the characteristics of the normal B cells that they are derived from, a feature that is frequently used in their diagnosis.