Publications by authors named "Cassandra Deichsel"
Demographic changes will expand the number of senior citizens suffering from Alzheimer's disease (AD). Key aspects of AD pathology are sleep impairments, associated with onset and progression of AD. AD mouse models may provide insights into mechanisms of AD-related sleep impairments.
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- Myelin, an insulating membrane produced by oligodendrocytes, enables fast action potential propagation in axons and is mostly formed early in development.
- Researchers used advanced imaging techniques to investigate structural and dynamic changes in myelin within the central nervous system during postnatal development in both mice and zebrafish.
- The study revealed that myelin experiences significant structural changes after birth, including degeneration processes managed by microglia and self-retraction mechanisms by oligodendrocytes, highlighting the complexity of myelin formation and refinement.