Publications by authors named "Cassandra Baker-Lee"
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Synopsis of recent research by authors named "Cassandra Baker-Lee"
- Cassandra Baker-Lee's recent research primarily focuses on improving the assay methodologies for antibody-drug conjugates (ADCs) and therapeutic monoclonal antibodies (mAbs), addressing challenges in accurately measuring these complex biomolecules.
- One key finding includes the development of a new version of the antibody-conjugated drug assay, specifically for valine-citrulline-linked monomethylauristatin E ADCs, enhancing characterization of their pharmacokinetics (PK) through more reliable measurements.
- Baker-Lee's studies also emphasize the advantages of dried blood spot (DBS) sampling over conventional serum and plasma collection methods, demonstrating that DBS can provide reproducible and precise quantification of therapeutic mAbs, facilitating more efficient blood sampling methods.
