Taking a systems approach to promote posttraumatic growth: A position paper.

As health systems emerge from the pandemic, academic medical centres are motivated to have a healthy and resilient workforce. In the face of the collective traumas of the pandemic, we took a systems approach to infuse wellness into our culture by modelling collective recovery in a non-traditional town hall. Over a dozen senior leaders, faculty, staff, and students shared their personal experiences in a virtual forum, nearly 1000 attendees communally supported one another.

Instagram as a virtual art display for medical students.

Implication Statement We require our medical students to create art as part of a core course. Projects have historically been displayed at our health sciences library. During a rapid adjustment to virtual teaching at the onset of the COVID-19 pandemic, using Instagram to hold a virtual art show was a quickly implemented alternative.

Tools for Discussing Identity and Privilege Among Medical Students, Trainees, and Faculty.

Introduction: Physicians and students of all backgrounds should be prepared to interact with patients of various socioeconomic, racial, ethnic, gender, religious, and sexual orientation identities. The approach described here emphasizes how important it is for physicians and physicians-in-training to develop self-awareness before engaging with patients.

Methods: Over the course of 6 months, we conducted workshops on identity awareness for four groups: (1) fourth-year medical students ( = 6), (2) first-year medical students ( = 88), (3) faculty and staff ( = 11), and (4) residents/fellows ( = 4).

Field Test Results of Sex- and Gender-Specific Health Multimedia Case-Based Learning Modules.

The sex- and gender-specific health (SGSH) multimedia case-based learning modules (MCBLMs) were developed to address the absence of validated or peer-reviewed material that incorporates topics of sex and gender differences into medical curricula. This article provides the methodology for development of the modules and reports the results of a field test of the modules in different medical educational settings. MCBLMs were created by a multidisciplinary committee of scientists, health profession educators, and students.

An empirical assessment of the short-term impacts of a reading of Deborah Zoe Laufer's drama Informed Consent on attitudes and intentions to participate in genetic research.

Objective: This study assessed the short-term impact of the play "Informed Consent" by Deborah Zoe Laufer (a fictionalized look at the controversy over specimens collected from the Havasupai Tribe for diabetes research in 1989) on perceptions of trust, willingness to donate biospecimens, and attitudes toward harm and privacy among the medical and undergraduate students, faculty, and the public in the Intermountain West.

Methods: Surveys were administered before and after a staged reading of the play by professional actors. Survey items included the short form Trust in Medical Researchers, and single-item questions about group identity, ethics of genetic testing in children, and willingness to donate biospecimens.

TETRA observation of gamma-rays at ground level associated with nearby thunderstorms.

[1] Terrestrial gamma-ray flashes (TGFs)-very short, intense bursts of electrons, positrons, and energetic photons originating from terrestrial thunderstorms-have been detected with satellite instruments. TGF and Energetic Thunderstorm Rooftop Array (TETRA), an array of NaI(Tl) scintillators at Louisiana State University, has now been used to detect similar bursts of 50 keV to over 2 MeV gamma-rays at ground level. After 2.

Perspective: The doctor as performer: a proposal for change based on a performance studies paradigm.

The authors recognize the pressing need for teaching methods that encourage empathy in both undergraduate and postgraduate medical curricula. While the useful application of theatrical acting techniques in medical education has been reported in major medical journals, these reports present an incomplete picture of these techniques and their potential importance to physician competence. The authors propose a broader understanding of performance theories and practices and a more nuanced appreciation of the experience and knowledge acquired through working with standardized patients and acting exercises.

Multiple peptides homologous to herpes simplex virus type 1 glycoprotein B inhibit viral infection.

The 773-residue ectodomain of the herpes simplex virus type 1 (HSV-1) glycoprotein B (gB) has been resistant to the use of mutagenic strategies because the majority of the induced mutations result in defective proteins. As an alternative strategy for the identification of functionally important regions and novel inhibitors of infection, we prepared a library of overlapping peptides homologous to the ectodomain of gB and screened for the ability of the peptides to block infection. Seven of 138 15-mer peptides inhibited infection by more than 50% at a concentration of 100 microM.

Physician Withdrawal Checklist (PWC-20).

Anxiety disorders are the most common mental illnesses in the United States. Despite having a number of medication options readily available, benzodiazepines (BZs) and antidepressants have achieved remission rates of only 35% after 8 weeks of acute treatment. In the development of new anxiolytics, particularly those that affect the gamma-aminobutyric acid system, it is essential to assess the new compound's potential to cause discontinuation symptoms after stopping the medication as part of both short- and long-term treatment.

Coordination of smooth pursuit and saccade target selection in monkeys.

The coordination of saccadic and smooth pursuit eye movements in macaque monkeys was investigated using a target selection paradigm with two moving targets crossing at a center fixation point. A task in which monkeys selected a target based on its color was used to test the hypothesis that common neural signals underlie target selection for pursuit and saccades, as well as testing whether target selection signals are available to the saccade and pursuit systems simultaneously or sequentially. Several combinations of target color, speed, and direction were used.

Laboratory calibration of the Extreme-Ultraviolet Imaging Spectrometer for the Solar-B satellite.

The laboratory end-to-end testing of the Extreme-Ultraviolet Imaging Spectrometer (EIS) for the Solar-B satellite is reported. A short overview of the EIS, which observes in two bands in the extreme-ultraviolet wavelength range, is given. The calibration apparatus is described, including details of the light sources used.

Vitreous glutamate concentration and axon loss in monkeys with experimental glaucoma.

Objective: To evaluate vitreous glutamate concentration and axon loss in monkeys with experimental glaucoma.

Methods: We induced unilateral chronic glaucoma by means of laser trabecular destruction in 14 rhesus and 6 cynomolgus monkeys. Intraocular pressure (IOP) was monitored weekly.

Atypical presentation of mycobacteriosis in a collection of frogfish (Antennarius striatus).

Severe systemic mycobacteriosis without typical granuloma formation was diagnosed in a group of six mature, captive, striated frogfish Antennarius striatus approximately 5 mo after fish originating from Brazil were purchased by Mote Marine Laboratory Aquarium. Beginning 1 mo after spawning, over a period of 9 mo, individuals began to show a variety of signs including egg retention, ocular opacity, poor buoyancy control, ascites with coelomic distension, skin lesions, and anorexia. Two fish died, and four were euthanatized.

Cortical spreading depression and involvement of the motor cortex, auditory cortex, and cerebellum in eyeblink classical conditioning of the rabbit.

The interrelationships of cerebellar and cerebral neural circuits in the eyeblink paradigm were explored with the controlled application of cortical spreading depression (CSD) and lidocaine in the New Zealand albino rabbit. The initial research focus was directed toward the involvement of the motor cortex in the conditioned eyeblink response. However, CSD timing and triangulation results indicate that other areas in the cerebral cortex, particularly the auditory cortex (acoustic conditioned stimulus), appear to be critical for the CSD effect on the eyeblink response.

Retinal glutamate in diabetes and effect of antioxidants.

Diabetes results in various biochemical abnormalities in the retina, but which of these abnormalities are critical in the development of retinopathy is not known. The aim of this study is to examine the effect of antioxidant supplementation on diabetes-induced alterations of retinal glutamate, and to explore the inter-relationship between alterations of retinal glutamate, oxidative stress, and nitric oxide (NO) in diabetes. Glutamate was measured in the retina at 2 months of diabetes in rats receiving diets supplemented with or without a mixture of antioxidants containing ascorbic acid, Trolox, DL alpha-tocopherol acetate, N-acetyl cysteine, beta-carotene and selenium.

Carisoprodol, meprobamate, and driving impairment.

This paper considers the pharmacology of the centrally acting muscle relaxant carisoprodol, and its metabolite meprobamate, which is also administered as an anxiolytic in its own right. Literature implicating these drugs in impaired driving is also reviewed. A series of 104 incidents in which these drugs were detected in the blood of drivers involved in accidents or arrested for impaired driving was considered, with respect to the analytical toxicology results, patterns of drug use in these subjects, the driving behaviors exhibited, and the symptoms observed in the drivers.

Use of image coregistration in salvage prostate brachytherapy.

Purpose: We describe a method of performing salvage prostate brachytherapy on patients whose initial implant was suboptimal. This technique uses an image correlation algorithm only previously used to fuse postimplant magnetic resonance and computed tomographic (CT) images. Here, the initial postimplant CT and the second preimplant volume study are coregistered to plan delivery of the salvage implant.