Publications by authors named "Casbas A"

Background And Aims: Despite the advances in medical therapies, a significant proportion of patients with inflammatory bowel diseases [IBD] require surgical intervention. This Topical Review aims to offer expert consensus practice recommendations for peri-operative care to optimize outcomes of IBD patients who undergo surgery.

Methods: A multidisciplinary panel of IBD healthcare providers systematically reviewed aspects relevant to peri-operative care in IBD.

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Article Synopsis
  • A study aimed to gather nationwide data on ulcerative colitis (UC) in Spain, focusing on its epidemiology and hospital resource usage among gastroenterology units.
  • The research, conducted in 2011 and involving multiple hospitals, found a prevalence rate of 88.7 UC cases per 100,000 inhabitants and an incidence rate of 5.7 cases per 100,000 inhabitants.
  • The results indicated that hospitalization rates for UC were low, with about 6% of patients hospitalized, and the majority of hospitals had specialized IBD units and access to colorectal surgeons.
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Background: Immune-mediated inflammatory diseases (IMIDs) are a group of complex and prevalent diseases where disease diagnostic and activity monitoring is highly challenging. The determination of the metabolite profiles of biological samples is becoming a powerful approach to identify new biomarkers of clinical utility. In order to identify new metabolite biomarkers of diagnosis and disease activity, we have performed the first large-scale profiling of the urine metabolome of the six most prevalent IMIDs: rheumatoid arthritis, psoriatic arthritis, psoriasis, systemic lupus erythematosus, Crohn's disease, and ulcerative colitis.

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Background: Recently, the notion that smoking may adversely affect Crohn's disease (CD) outcomes has been challenged by the suggestion that the widespread use of immunosuppressants and anti-TNF drugs might offset the adverse effects of tobacco.

Aim: To reassess the influence of tobacco smoking on disease phenotype and complications on a time-dependent analysis, taking into account the different therapeutic interventions.

Methods: We designed a retrospective cohort study of 3224 patients with Crohn's disease.

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