Determinants of the onset and prognosis of the post-COVID-19 condition: a 2-year prospective observational cohort study.

Background: At least 5-10% of subjects surviving COVID-19 develop the post-COVID-19 condition (PCC) or "Long COVID". The clinical presentation of PCC is heterogeneous, its pathogenesis is being deciphered, and objective, validated biomarkers are lacking. It is unknown if PCC is a single entity or a heterogeneous syndrome with overlapping pathophysiological basis.

PSON: A Serialization Format for IoT Sensor Networks.

In many Internet of Things (IoT) environments, the lifetime of a sensor is linked to its power supply. Sensor devices capture external information and transmit it. They also receive messages with control commands, which means that one of the largest computational overheads of sensor devices is spent on data serialization and deserialization tasks, as well as data transmission.

Acute calciphylaxis precipitated by the initiation of hemodialysis.

Calciphylaxis, or calcific uremic arteriopathy (CUA), is characterized by metastatic calcification in the media of small arteries and arterioles leading to cutaneous necrosis. It is most commonly seen in patients with end stage renal disease who have elevated serum calcium × phosphorus (Ca × P) product. Normalization of Ca × P product is considered paramount in the prevention and treatment of CUA.

Diffuse alveolar haemorrhage in ANCA-negative pauci-immune crescentic glomerulonephritis.

Pulmonary renal syndrome (PRS) is a combination of diffuse pulmonary haemorrhage and glomerulonephritis (GN). Though an established form of presentation in anti-neutrophil cytoplasmic autoantibody (ANCA)-associated GN and vasculitis, diffuse pulmonary haemorrhage is extremely unusual in those with ANCA-negative GN. We present here a case of a 76-year-old Hispanic female with stage IV chronic kidney disease (serum creatinine of 2 mg/dL), who presented with diffuse alveolar haemorrhage and nephritic syndrome.

Nosocomial valve endocarditis due to corynebacterium striatum: a case report.

Staphylococcus aureus, Coagulase-negative staphylococci, and Enterococci sp. are the usual pathogens involved in nosocomial bacterial endocarditis. Corynebacterium species isolation in blood specimens is usually considered to be a contaminant.

Over a millon Creatine Kinase due to a heavy work-out: A case report.

Rhabdomyolysis induced by exercise is a very well known entity, several cases has been reported in the literature related with strenuous activities, weight lifting, marathon running, overexertion in an untrained person, knee bends, etc. We reported an interesting case of exercise-induced rhabdomyolysis in a 25 year old Hispanic male, after resuming his regular physical activity, with the highest creatine kinase described in the literature, successfully treated with aggressive hydration only and no complications.

The misuse of the three-point cross for estimating chiasma interference.

The building of genetic maps in diploid organisms by crosses between different genotypes and estimation of recombination frequencies from the obtained segregation data has been successfully used since a very young step in the birth of genetics. The three-point cross methodology has facilitated this task and has demonstrated at the same time that genetic distances are not additive, as some recombinant products are not recognised in the progeny. Three-point cross also allows to examine if chiasma interference exists and its evaluation.

Involvement of cuticular hydrocarbons in the mating success of Drosophila melanogaster females.

The role of Drosophila melanogaster female pheromones in mating success was investigated in parallel with female receptivity. Lines selected for high and low female receptivity showed no changes in the patterns of cuticular hydrocarbons despite the occurrence of large variation for these aphrodisiac compounds in the base population. Female mating success was clearly related to receptivity level but not to pheromone-mediated attractiveness.

A corrected Haldane's map function to calculate genetic distances from recombination data.

The estimation of genetic distances from recombination data has no direct relationship due to the fact that multiple crossovers do not generate recombinant gametes that can be recognized in the progeny. The Haldane's map function is the most widely used mathematical formulation able to relate the observed recombination frequency with the actual number of crossovers. Here I show that the model in which the Haldane's correction is based on is not correct, and I present a modified map function that takes into consideration the actual number of recombinant gametes produced in cells in which different number of crossovers have occurred.

Is premating isolation in Drosophila overestimated due to uncontrolled factors?

Sexual isolation in Drosophila is typically measured by multiple-choice mating tests. While many environmental variables during such tests are controlled by the researcher, there are some factors that are usually uncontrolled. We demonstrate, using Drosophila melanogaster and D.

Genetics of Drosophila simulans male mating discrimination in crosses with D. melanogaster.

The genetic bases of sexual isolation between Drosophila melanogaster and D. simulans have been mainly studied in females, and there is little information about the role of the males in interspecific mating discrimination. Using D.

An investigation of the attachment organization of clinical psychologists and its relationship to clinical practice.

Recent research on attachment theory as a model for understanding adult relationships and for psychotherapy suggests that the attachment organization of therapists could influence their approach to therapeutic work. A postal questionnaire including two measures of current adult attachment and one of early loss experience, together with measures of current clinical practice, was completed by 196 British clinical psychologists (40.4% return rate).

Sexual isolation between Drosophila melanogaster, D. simulans and D. mauritiana: sex and species specific discrimination.

The sexual isolation among the related species Drosophila melanogaster, D. simulans and D. mauritiana is asymmetrical.

Location of Shfr, a new gene that rescues hybrid female viability in crosses between Drosophila simulans females and D. melanogaster males.

As a rule, progeny of crosses between Drosophila simulans females and D. melanogaster males are formed by sterile males, because females die as embryos. However, populations of these species have been found that produce a certain frequency of viable hybrid females.

Inheritance mode of Drosophila simulans female mating propensity with D. melanogaster males.

The genetic factors involved in the sexual isolation between Drosophila simulans females and D. melanogaster males are hardly known. We present a study of female mating propensity of D.

Genetics of hybridization between Drosophila simulans females and D. melanogaster males.

Drosophila simulans and D. melanogaster are sibling cosmopolitan species with imperfect ethological isolation. Hybridization is easy between D.

DISENTANGLING THE EFFECTS OF MATING PROPENSITY AND MATING CHOICE IN DROSOPHILA.

Incipient sexual isolation between genotypes, lines, or populations of the same species is commonly measured in Drosophila by choice tests. Results of these tests are known to be influenced, in an undetermined manner, by the mating propensity of competitors and by discriminatory factors during courtship. We have approached the problem by measuring male and female propensities in separate, independent tests, and by examining whether these estimates could explain the results of the choice tests.

Chromosomal substitution analysis of receptivity and sexual isolation in Drosophila melanogaster females.

A chromosome substitution analysis was carried out in Drosophila melanogaster to elucidate the contribution of the X, II and III chromosomes to female receptivity, and to sexual isolation with its sibling species D. simulans. Two lines from the same base population with extreme phenotypes, the one showing high receptivity and weak isolation and the other showing low receptivity and strong isolation, were used.

Sexual isolation between Drosophila melanogaster females and D. simulans males. Male mating propensities versus success in hybridization.

Genetic variation has been found in males of a D. simulans population for their eagerness to hybridize with D. melanogaster females.

Male mating speed in Drosophila melanogaster: differences in genetic architecture and in relative performance according to female genotype.

From a critical review of the literature on mating speed in Drosophila, the importance of fast mating in male fitness is questioned. The genetic architecture of male mating speed (MMS) has been evaluated in D. melanogaster through a populational analysis and a full 5 x 5 diallel cross between inbred lines.

Bidirectional selection for female receptivity in Drosophila melanogaster.

A wild population of Drosophila melanogaster was subjected to selection for high and low female receptivity. Selection was only applied in females on the basis of the mating times observed in a 30-min period. We applied a selection paradigm that allowed us to conclude that females unmated after 30 min correspond to the truncated upper tail of the distribution underlying mating times.

Genetic basis for female receptivity in Drosophila melanogaster: a diallel study.

Receptivity of sexually mature, virgin females, measured as the time to copulation, has been investigated. Two independent 5 x 5 diallel crosses were carried out, each one with a different male tester genotype. Interactions between male and female genotypes were detected because some lines appeared as dominant in one diallel and recessive in the other.

Response to selection for increased hybridization between Drosophila melanogaster females and D. simulans males.

Females of Drosophila melanogaster and males of D. simulans hybridizing in a nonchoice condition were artificially selected for 12 generations. The frequency of hybridization increased from 10% to 79%.

Selection for pupation height in Drosophila melanogaster.

Divergent directional selection for high and low pupation height was practiced in D. melanogaster. A quick response was observed in the two directions of selection.