Chronic active lesions preferentially localize in watershed territories in multiple sclerosis.

Objective: Paramagnetic rim lesions (PRLs) are a biomarker of chronic active lesions (CALs), and an important driver of neurological disability in multiple sclerosis (MS). The reason subtending some acute lesions evolvement into CALs is not known. Here we ask whether a relatively lower oxygen content is linked to CALs.

A preliminary study on the variability of blood glucose following meal consumption as it relates to differences in oral glucose tolerance in young adults.

Insulin resistance (IR) affects the ability to maintain normal glycemia and places one at greater risk of the development of disease. The aim of this study was to assess IR via the administration of an oral glucose tolerance test (OGTT) and then determine the relationship between IR and postprandial blood glucose levels in young adults 19-24 years of age. Following a 10 hour fast, 10 men and 10 women completed an OGTT and in three subsequent weeks consumed high, medium, and low glycemic load (GL) meals in random order.