Hormonal Contraceptive Use and Physical Performance, Body Composition, and Musculoskeletal Injuries during Military Training.

Purpose: To investigate associations between hormonal contraceptive use and physical performance, body composition, and musculoskeletal injuries in basic military training.Methods: Female British Army recruits (n = 450) were grouped as non-users (n = 182), combined oral contraceptive users (COCP; n = 184), or progestin-only users (POC; n = 144). Physical performance (2.

Iron status is associated with tibial structure and vitamin D metabolites in healthy young men.

The influence of iron on collagen synthesis and vitamin D metabolism has implications for bone health. This cross-sectional observational study investigated associations between markers of iron status and tibial structure, vitamin D metabolites, and circulating biochemical markers of bone metabolism in young healthy men. A total of 343 male British Army recruits participated (age 22 ± 3 y, height 1.

Sex differences in iron status during military training: a prospective cohort study of longitudinal changes and associations with endurance performance and musculoskeletal outcomes.

This study investigated sex differences in Fe status, and associations between Fe status and endurance and musculoskeletal outcomes, in military training. In total, 2277 British Army trainees (581 women) participated. Fe markers and endurance performance (2·4 km run) were measured at the start (week 1) and end (week 13) of training.

Vitamin D Metabolites Are Associated With Musculoskeletal Injury in Young Adults: A Prospective Cohort Study.

The relationship between vitamin D metabolites and lower body (pelvis and lower limb) overuse injury is unclear. In a prospective cohort study, we investigated the association between vitamin D metabolites and incidence of lower body overuse musculoskeletal and bone stress injury in young adults undergoing initial military training during all seasons. In 1637 men and 530 women (aged 22.

Effects of hotter, drier conditions on gaseous losses from nitrogen fertilisers.

Global warming is expected to cause hotter, drier summers and more extreme weather events including heat waves and droughts. A little understood aspect of this is its effects on the efficacy of fertilisers and related nutrient losses into the environment. We explored the effects of high soil temperature (>25 °C) and low soil moisture (<40% water filled pore space; WFPS) on emissions of ammonia (NH) and nitrous oxide (NO) following application of urea to soil and the efficacy of urease inhibitors (UI) in slowing N losses.

Distal Tibial Bone Properties and Bone Stress Injury Risk in Young Men Undergoing Arduous Physical Training.

Trabecular microarchitecture contributes to bone strength, but its role in bone stress injury (BSI) risk in young healthy adults is unclear. Tibial volumetric BMD (vBMD), geometry, and microarchitecture, whole-body areal BMD, lean and fat mass, biochemical markers of bone metabolism, aerobic fitness, and muscle strength and power were measured in 201 British Army male infantry recruits (age 20.7 [4.

The mediation effect of indoor air quality on health: A comparison of homeowners and renters.

This research aims to explore whether there is a health disparity between homeowners and renters affected by the indoor air quality of their dwellings. By proxying the presence of mold and smoke as conjoint facilitators of poor indoor air quality, we design a mediation model that previously has not been explored empirically. The structural path model in this study shows that there is indeed a disparity in health between homeowners and renters by demography, socioeconomic status, and dwelling condition.

Vitamin D Metabolites Are Associated with Physical Performance in Young Healthy Adults.

Purpose: This study aimed to determine vitamin D metabolites and vitamin D receptor (VDR) single-nucleotide polymorphism (SNP) relationships with physical performance.

Methods: In 1205 men and 322 women (94.8% White Caucasian, 22.

An Inducible and Vascular Smooth Muscle Cell-Specific Pink1 Knockout Induces Mitochondrial Energetic Dysfunction during Atherogenesis.

DNA damage and mitochondrial dysfunction are defining characteristics of aged vascular smooth muscle cells (VSMCs) found in atherosclerosis. Pink1 kinase regulates mitochondrial homeostasis and recycles dysfunctional organelles critical for maintaining energetic homeostasis. Here, we generated a new vascular-specific Pink1 knockout and assessed its effect on VSMC-dependent atherogenesis and VSMC energetic metabolism .

Teriparatide and stress fracture healing in young adults (RETURN - Research on Efficacy of Teriparatide Use in the Return of recruits to Normal duty): study protocol for a randomised controlled trial.

Background: Stress fractures are a common and potentially debilitating overuse injury to bone and occur frequently among military recruits and athletes. Recovery from a lower body stress fracture typically requires several weeks of physical rehabilitation. Teriparatide, a recombinant form of the bioactive portion of parathyroid hormone (1-34 amino acids), is used to treat osteoporosis, prevent osteoporotic fractures, and enhance fracture healing due to its net anabolic effect on bone.

The Impact of U.S. Housing Type and Residential Living Situations on Mental Health during COVID-19.

Residential environments could be associated with the mental health of residents, in general, and during the COVID-19 pandemic. However, limited studies have investigated the relationship between these two. This study used data from the Household Pulse Survey, collected between 23 April 2020 and 23 November 2020 to explore the relationship between mental health status as perceived by the residents and housing tenure (own or rent), building type, and the number of household members, while accounting for sociodemographic characteristics, general health-related variables, and week-specific unobserved heterogeneities.

A Pilot Outreach HIV Testing Project Among Homeless Adults.

The Memphis metropolitan statistical area (MSA) represents a Deep Southern U.S. city disproportionally affected by the ongoing transmission of new HIV cases as well as those diagnosed in late-stage disease.

Smoking Cessation among Pregnant and Postpartum Women from Low-Income Groups in the United States.

Introduction: Pregnancy creates a unique window of opportunity for smoking cessation. However, pregnant women from underserved groups can face personal, social, and environmental challenges that impede quitting. This study draws upon the socioecological framework to explore perspectives on smoking cessation among pregnant and postpartum women from low-income groups in the mid-South of the United States.

Influence of Vitamin D Supplementation by Simulated Sunlight or Oral D3 on Respiratory Infection during Military Training.

Purpose: This study aimed to determine the relationship between vitamin D status and upper respiratory tract infection (URTI) of physically active men and women across seasons (study 1) and then to investigate the effects on URTI and mucosal immunity of achieving vitamin D sufficiency (25(OH)D ≥50 nmol·L-1) by a unique comparison of safe, simulated sunlight or oral D3 supplementation in winter (study 2).

Methods: In study 1, 1644 military recruits were observed across basic military training. In study 2, a randomized controlled trial, 250 men undertaking military training received placebo, simulated sunlight (1.

Veterinary-prescribed physical activity promotes walking in healthy dogs and people.

Background: Regular physical activity (PA) promotes health and can prevent and treat diseases among both humans and dogs. Unfortunately, most U.S.

Striking a balance between N sources: Mitigating soil acidification and accumulation of phosphorous and heavy metals from manure.

Manure amendment has been shown to effectively prevent red soil (Ferralic Cambisol) acidification from chemical nitrogen (N) fertilization. However, information is lacking on how much manure is needed to mitigate acidification and maintain soil productivity while preventing accumulation of other nutrients and heavy metals from long-term inputs. This study determined the effects of various combinations of manure with urea-N on acidification and changes in soil P, K, and heavy metals in a 9-year maize field experiment in southern China.

Changes in soil organic carbon status and microbial community structure following biogas slurry application in a wheat-rice rotation.

Biogas slurry is widely used as a crop fertilizer due to its available nitrogen content. However, it remains unclear how biogas slurry application affects soil organic carbon (SOC) status and soil microbial community under typical agricultural systems. Here, under a wheat-rice field experiment, we examined the responses of SOC and soil bacterial and fungal communities to biogas slurry application, both with (BSS) and without (BS) straw return, relative to chemical nitrogen fertilizer with (CFS) and without (CF) straw return.

Process and Outcome Evaluation of a Mindfulness-Based Cognitive Therapy Intervention for Cisgender and Transgender African American Women Living with HIV/AIDS.

There is a need for evidence-based contextualized mental health interventions for persons living with HIV/AIDS. In the current study, the primary researcher conducted open trials with African American women living with HIV/AIDS (AAWLWHA) to examine the acceptability and feasibility of Project UPLIFT, a mindfulness-based cognitive therapy intervention that has demonstrated effectiveness in persons living with epilepsy. Women were recruited for a tele-delivered phone intervention group separated by gender identity, as well as participated in pre- and post-test assessments.

Fate and transfer of heavy metals following repeated biogas slurry application in a rice-wheat crop rotation.

The application of biogas slurry, from anaerobic digestion of livestock excreta, to cropland has proven to be an effective mechanism for recycling nutrients within farms. However, the potential pollution of heavy metals from repeated biogas slurry fertilization has not received much attention. Here we present the results of a field experiment under rice-wheat rotation demonstrating the accumulation, speciation distribution and plant uptake of heavy metals (Cu, Zn, Pb and Cd) in soil following biogas slurry application.

Vitamin D and the hepatitis B vaccine response: a prospective cohort study and a randomized, placebo-controlled oral vitamin D and simulated sunlight supplementation trial in healthy adults.

Purpose: To determine serum 25(OH)D and 1,25(OH)D relationship with hepatitis B vaccination (study 1). Then, to investigate the effects on hepatitis B vaccination of achieving vitamin D sufficiency (serum 25(OH)D ≥ 50 nmol/L) by a unique comparison of simulated sunlight and oral vitamin D supplementation in wintertime (study 2).

Methods: Study 1 involved 447 adults.

The effect of caffeine on cognitive performance is influenced by CYP1A2 but not ADORA2A genotype, yet neither genotype affects exercise performance in healthy adults.

Purpose: To determine the influence of two commonly occurring genetic polymorphisms on exercise, cognitive performance, and caffeine metabolism, after caffeine ingestion.

Methods: Eighteen adults received caffeine or placebo (3 mg kg) in a randomised crossover study, with measures of endurance exercise (15-min cycling time trial; 70-min post-supplementation) and cognitive performance (psychomotor vigilance test; PVT; pre, 50 and 95-min post-supplementation). Serum caffeine and paraxanthine were measured (pre, 30 and 120-min post-supplementation), and polymorphisms in ADORA2A (rs5751876) and CYP1A2 (rs762551) genes analysed.

Effects of urease and nitrification inhibitors on soil N, nitrifier abundance and activity in a sandy loam soil.

Inhibitors of urease and ammonia monooxygenase can limit the rate of conversion of urea to ammonia and ammonia to nitrate, respectively, potentially improving N fertilizer use efficiency and reducing gaseous losses. Winter wheat grown on a sandy soil in the UK was treated with urea fertilizer with the urease inhibitor N-(n-butyl) thiophosphoric triamide (NBPT), the nitrification inhibitor dicyandiamide (DCD) or a combination of both. The effects on soil microbial community diversity, the abundance of genes involved in nitrification and crop yields and net N recovery were compared.

Impact of transition from permanent pasture to new swards on the nitrogen use efficiency, nitrogen and carbon budgets of beef and sheep production.

There is currently much debate around the environmental implications of ruminant farming and a need for robust data on nitrogen (N) and carbon (C) fluxes from beef and sheep grazing systems. Here we use data collected from the North Wyke Farm Platform along with the SPACSYS model to examine the N and C budgets and the N use efficiency (NUE) of grassland swards at different stages of establishment. We assessed the transition from permanent pasture (PP) to a high-sugar grass (HSG), and a mixed sward of HSG with white clover (HSGC), identifying data specifically for the reseed (RS) years and the first year following RS (HSG-T and HSGC-T).

Assessing the Acceptability of a Mindfulness-Based Cognitive Therapy Intervention for African-American Women Living with HIV/AIDS.

African-American HIV-seropositive women are at elevated risk for depressive symptoms compared to their seropositive counterparts. Depressive symptoms have been linked to HIV/AIDS-related health predictors and outcomes such as medication and care adherence, and viral load. Project UPLIFT, a mindfulness-based cognitive therapy intervention originally designed for persons with epilepsy has been shown effective to reduce depressive and anxiety symptoms.