The first intermediates in the bromination of bicyclo[3.3.1]nonylidenebicyclo[3.3.1]nonane, combination of experiments and theoretical results.

Bicyclo[3.3.1]nonylidenebicyclo[3.

Tweezing-adsorptive bubble separation. Analytical method for the selective and high enrichment of metalloenzymes.

A novelly developed tweezing-adsorptive bubble separation (ABS) method for the enrichment of metalloenzymes (laccase C and horseradish peroxidase) is introduced. The method is based on the chelation of the enzymes' active center and can also be applied for analysis. N-(2-acetamido)iminodiacetic acid served as a chelator and was synthesized with an octyl unit to become ADA-C8.

Reactivity of homoallylic substituted adamantylideneadamantanes with bromine. Substituent effects on the stability of the ionic and nonionic intermediates.

Sterically congested adamantylideneadamantanes (1b-g) (X = Br, Cl, F, OH, OEt, OCOCH(3)), homoallylically substituted with equatorial groups (X), react with bromine in 1,2-dichloroethane to give a stable bromonium ion intermediate or a substitution product depending on the nature of the substituent and on the bromine concentration. The nature of the substituent markedly affects the formation constant of the 1:1 pi-complexes, as well as of the formation constant and reactivity of bromonium ion intermediates. The different reactivity of the ionic intermediates, which depends on the nature of substituents, is attributed to bromonium or bromocarbenium character of the intermediate, with the support of theoretical investigations.