Publications by authors named "Carsten Holm"

Article Synopsis
  • The study investigated the impact of an 8-week preoperative low-load blood flow restricted resistance training (BFR-RT) program on knee osteoarthritis (OA) patients scheduled for total knee arthroplasty (TKA) compared to conventional care with no exercise.
  • Results showed no significant differences in physical function or patient-reported outcomes between the BFR-RT and the usual care group at 3 and 12 months post-surgery.
  • However, BFR-RT led to notable improvements in lower limb strength at 3 months postoperatively, indicating that it may enhance muscle strength but not necessarily overall physical function post-TKA.
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Background: Bone marrow lesions (BMLs) in knee osteoarthritis (OA) have been assessed histopathologically and by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI); however, a direct comparison of the results has not been reported.

Purpose: To evaluate and compare the findings by DCE-MRI and histopathology of subchondral BMLs in knee OA.

Material And Methods: In total, 19 patients with medial tibiofemoral knee OA undergoing total knee arthroplasty were analyzed.

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Background: Approximately 20% of patients undergoing total knee arthroplasty (TKA) do not experience long-term improvements. Our aim was to identify prognostic factors of knee pain and function 12 months after TKA.

Methods: In a prospective cohort study, 1026 patients underwent primary TKA between 2018 and 2020.

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Background And Purpose: Despite increased attention to and acceptance of fast-track procedures, there is a lack of studies concerning discharge on the day of surgery (DOS) following total knee arthroplasty (SD-TKA). We evaluated the feasibility of SD-TKA, and compared safety and patient-reported outcomes (PROs) between patients undergoing SD-TKA and patients undergoing standard TKA.

Patients And Methods: A SD-TKA group (n = 101) was matched 1:1 to a standard TKA group (n = 101) on age, sex, and ASA score.

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Introduction: Many patients with knee osteoarthritis referred to orthopaedic surgeons are not eligible for surgery and might benefit from being examined by other healthcare professionals. The objective of this study was to develop and test a screening algorithm to define relevant referral to the OS.

Methods: Prior to clinical examination, 173 consecutive patients referred to the orthopaedic outpatient clinic completed questionnaires, and radiographic osteoarthritis severity was graded.

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Background And Objectives: High-dose intravenous dexamethasone reduces the postoperative opioid requirement and is often included in the multimodal analgesia strategy after total knee arthroplasty (TKA). Combined obturator nerve and femoral triangle blockade (OFB) reduces the opioid consumption and pain after TKA better than local infiltration analgesia (LIA). The question is whether preoperative high-dose intravenous dexamethasone would cancel out the superior analgesic effect of OFB compared with LIA.

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Background And Purpose: It is unclear whether mobile-bearing (MB) total knee arthroplasties reduce the risk of tibial component loosening compared to fixed-bearing (FB) designs. This randomized study investigated implant migration, periprosthetic bone mineral density (BMD), and patient-reported outcomes (Oxford knee score)-all at 2 years-for the P.F.

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Background: Major trauma presents major diagnostic and therapeutic problems. Any delay in providing the treatment necessary may lead to increased morbidity and mortality, prolonged length of hospital stay, and increased cost. This study was undertaken to determine the extent, contributing factors, and implication of missed injuries and relate them to the three surveys in a Danish Level I trauma center.

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