Publications by authors named "Carson Woodbury"
Prevention of Postoperative Constipation in Urogynecology Patients: A Systematic Review.
Urogynecology (Phila)
February 2023
Importance: Constipation is common after pelvic surgery, and studies suggest that surgeons underestimate the negative impact of constipation on patients. Patients undergoing pelvic reconstructive surgery are a unique population requiring special consideration in the prevention and management of constipation.
Objective: This study aimed to systematically review the literature to identify evidence for prevention of postoperative constipation with medications or fiber in patients undergoing reconstructive pelvic surgery.
Article Synopsis
- Sacrospinous ligament fixation is a surgical procedure for prolapse repair, and this study aimed to compare 30-day complication rates based on the type of anesthesia used (general vs. regional).
- The analysis included data from nearly 3,000 cases from 2015 to 2020, finding that most were done under general anesthesia, with differences in patient demographics and some complications noted for the regional anesthesia group.
- Ultimately, the study concluded that the type of anesthesia did not significantly affect complication rates, but highlighted the need to further explore racial and ethnic disparities in anesthesia selection.
Background: Universal screening for SARS-CoV-2 infection on Labor and Delivery (L&D) units is a critical strategy to manage patient and health worker safety, especially in a vulnerable high-prevalence community. We describe the results of a SARS-CoV-2 universal screening program at the L&D Unit at Elmhurst Hospital in Queens, NY, a 545-bed public hospital serving a diverse, largely immigrant and low-income patient population and an epicenter of the global pandemic.
Methods And Findings: We conducted a retrospective cross-sectional study.
Genomic instability contributes to a variety of potentially damaging conditions, including DNA-based rearrangements. Breakage in the form of double strand breaks (DSBs) increases the likelihood of DNA damage, mutations and translocations. Certain human DNA regions are known to be involved in recurrent translocations, such as the palindrome-mediated rearrangements that have been identified at the breakpoints of several recurrent constitutional translocations: t(11;22)(q23;q11), t(17;22)(q11;q11) and t(8;22) (q24;q11).
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- The study aimed to compare the tensile strength of the native scapholunate ligament (SLL) with an all-suture anchor construct using a cadaver model.
- The researchers found that the mean peak load-to-failure for the native SLL was 273 N, while the all-suture anchor construct had a mean of 172 N, which is about 75% of the native strength.
- The difference in tensile strength between the two was not statistically significant (p = 0.157), suggesting that while the sutures are weaker, they are still comparable to the native ligament.
An essential step for understanding the transcriptional circuits that control development and physiology is the global identification and characterization of regulatory elements. Here, we present the first map of regulatory elements across the development and ageing of an animal, identifying 42,245 elements accessible in at least one stage. Based on nuclear transcription profiles, we define 15,714 protein-coding promoters and 19,231 putative enhancers, and find that both types of element can drive orientation-independent transcription.
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