An MRI/US/x-ray compatible breast localization marker: in vivo evaluation.

Rationale And Objectives: An in vivo evaluation of a new trimodality breast localization marker was performed with magnetic resonance imaging (MRI), ultrasound (US), x-ray, and histopathology. The evaluation of the marker in animal tests should help define its utility for surgical biopsy localization in humans.

Materials And Methods: Five rabbits were used and sacrificed at 2 days, 1 week, 2 weeks, 4 weeks, and 7 weeks after marker implantation.

Usefulness of contrast kinetics for predicting and monitoring tissue changes in muscle following thermal therapy in long survival studies.

Purpose: To investigate Gd-DTPA kinetics as indicators of subacute and subchronic histopathological changes following focused ultrasound (FUS) thermal therapy for improved evaluation.

Materials And Methods: A total of 18 FUS lesions were created in the thigh muscle of five rabbits under magnetic resonance (MR) guidance at 1.5 Tesla.

Prediction of subtle thermal histopathological change using a novel analysis of Gd-DTPA kinetics.

Purpose: To investigate Gd-DTPA kinetics as predictors of histopathological changes following focused ultrasound (FUS) thermal ablation for improved planning and assessment.

Materials And Methods: Twenty-nine FUS lesions were created in the thigh muscle of eight rabbits under MR-guidance at 1.5 Tesla.