Synopsis of recent research by authors named "Carrie L Fuertes"
- Carrie L Fuertes' research focuses on improving the detection and analysis of circulating tumor DNA (ctDNA) in cancer, specifically pancreatic ductal adenocarcinoma (PDAC), using advanced next-generation sequencing (NGS) techniques.
- Findings indicate that addressing NGS noise is crucial for accurate ctDNA identification, revealing that pre-operative ccfDNA analysis can provide significant prognostic insights in cancer patients.
- Fuertes highlights the importance of methodological advancements, such as automated size selection of cell-free DNA fragments and the use of sample duplicates, in enhancing the reliability and accuracy of ctDNA detection and variant analysis in clinical applications.
