Publications by authors named "Carrie Kah-Lai Leong"

Persistent air leak may complicate malignant disease of the thorax, causing significant morbidity and mortality. A 51-year-old male with a 30-pack-year history of smoking was diagnosed with metastatic esophageal carcinoma with invasion into the right upper lobe of the lung. He developed a large right hydropneumothorax complicated by empyema leading to persistent air leak despite the insertion of two chest drains.

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Massive hemoptysis is a time critical airway emergency in the perioperative setting, with an associated mortality exceeding 50%. Causes of hemoptysis in the perioperative setting include procedural complication, coagulopathy, malignancy, chronic lung disease, infection, left-sided cardiac disease, pulmonary vascular disease and autoimmune disease. A rapid and coordinated multidisciplinary response is required to secure the airway, isolate the lung, ensure adequate oxygenation and ventilation, identify the underlying cause and initiate specific systemic, bronchoscopic, endovascular, or surgical treatment.

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Article Synopsis
  • The study evaluates the effectiveness and safety of medical thoracoscopy (MT) for diagnosing malignant pleural effusions (MPEs) in 141 patients from January 2020 to December 2022 at a tertiary hospital.
  • It found a high diagnostic accuracy of 95.7%, with lung and breast cancers being the most frequently diagnosed types, and molecular profiling for cancer mutations was successfully completed for all malignancy cases.
  • Major complications were rare, occurring in only 2.1% of patients, and overall, MT proved to be a safe and beneficial procedure in managing suspected MPEs without significant adverse outcomes.
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Background: Survival in cardiac arrest is associated with rapid initiation of high-quality cardiopulmonary resuscitation (CPR) and advanced life support. To improve ROSC rates and survival, we identified the need to reduce response times and implement coordinated resuscitation by dedicated cardiac arrest teams (CATs). We aimed to improve ROSC rates by 10% within 6 months, and subsequent survival to hospital discharge.

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Methods: We conducted a retrospective review of patients with pleural infection requiring intrapleural therapy at two tertiary referral centres.

Results: We included 84 (62.2%) and 51 (37.

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Background: In advanced esophageal carcinoma (EC), there is limited data on risk factors predicting tracheobronchoesophageal fistula (TEF) formation and survival among patients who required airway interventions.

Methods: A retrospective analysis of consecutive patients with EC, who had airway involvement requiring intervention, was conducted from 1998 to 2018. Demographics, clinical progress, disease stage, treatment and survival outcomes were recorded.

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The coronavirus disease 2019 (COVID-19) has rapidly evolved into a worldwide pandemic. Preparing intensive care units (ICU) is an integral part of any pandemic response. In this review, we discuss the key principles and strategies for ICU preparedness.

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