Evaluation of smartphone-based cough data in amyotrophic lateral sclerosis as a potential predictor of functional disability.

Objectives: Cough dysfunction is a feature of patients with amyotrophic lateral sclerosis (ALS). The cough sounds carry information about the respiratory system and bulbar involvement. Our goal was to explore the association between cough sound characteristics and the respiratory and bulbar functions in ALS.

Voice Assessment in Patients with Amyotrophic Lateral Sclerosis: An Exploratory Study on Associations with Bulbar and Respiratory Function.

Background: Speech production is a possible way to monitor bulbar and respiratory functions in patients with amyotrophic lateral sclerosis (ALS). Moreover, the emergence of smartphone-based data collection offers a promising approach to reduce frequent hospital visits and enhance patient outcomes. Here, we studied the relationship between bulbar and respiratory functions with voice characteristics of ALS patients, alongside a speech therapist's evaluation, at the convenience of using a simple smartphone.

Clinical epidemiological and laboratory investigation in co-infection with COVID-19 and tuberculosis.

Currently, COVID-19 and tuberculosis (TB) are the deadliest infectious diseases worldwide. Their synergy, form of presentation, morbidity, and mortality are data that have been scarcely explored. Thus, this study aimed to characterize the clinical, epidemiological, and laboratory factors of this co-infection and to analyze the factors associated with the active TB among COVID-19 cases.

Elexacaftor/tezacaftor/ivacaftor, a game-changer in cystic fibrosis: The Portuguese experience.

Background: Phase 3 trials of elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) combination treatment in people with cystic fibrosis (CF) with ≥1 F508del-CFTR allele showed profound short-term effects on lung function, weight, and pulmonary exacerbations (PEx). The authors conducted a 12-month study to add evidence on the real-world long-term effectiveness and safety of CFTR modulator therapy with ELX/TEZ/IVA in Portuguese CF adult population.

Methods: Ambispective, multicentre, observational, real-life study involving all the Portuguese CF Reference Centres.

Effects of UV Postcuring Times on the Color Stability, Surface Properties and Conversion of 3D-printed Temporary Resin Composites.

Objective: To evaluate the effects of UV postcuring times on color stability (CS), surface properties (wettability [°] and surface roughness [Ra]), and conversion of 3D-printed resins for temporary restorations.

Methods: Disc-shaped specimens (10.0×3.

Cryptic diversity of shallow and mesophotic Stephanocoenia intersepta corals across Florida Keys National Marine Sanctuary.

Population genetic analyses can provide useful data on species' regional connectivity and diversity which can inform conservation and restoration efforts. In this study, we quantified the genetic connectivity and diversity of Stephanocoenia intersepta corals from shallow (<30 m) to mesophotic (30-45 m) depths across Florida Keys National Marine Sanctuary. We generated single nucleotide polymorphism (SNP) markers to identify genetic structuring of shallow and mesophotic S.

Effect of Cantilever Extension on Bone Loss in Mandibular Complete-Arch Implant-Supported Fixed Prostheses with Three and Four Implants.

Purpose: To compare the peri-implant bone loss of mandibular complete-arch implant-supported fixed prostheses (FPSs) supported by three and four implants and to correlate with the size of the horizontal and vertical distal cantilever at prosthesis placement (T1) and after 1 year (T2).

Materials And Methods: A total of 72 external hexagon (EH) type implants were placed in 20 participants. Of these, 24 supported an FPS with three implants (G3I) and 48 with four implants (G4I).

Maxillomandibular relationship record methods for computer-engineered complete dentures: a scoping review.

Objectives: The purpose of this scoping review was to identify different methods employed for recording the maxillomandibular relationship (MMR) for computer-aided designed and manufactured (CAD-CAM) complete dentures (CDs).

Materials And Methods: This scoping review followed the PRISMA-ScR guidelines and was developed according to Arksey and O'Malley and The Joanna Briggs Institute protocol. The methods were registered on the Open Science Framework (< osf.

Conventional and digital maxillary occlusal record for the manufacture of complete-arch implant-supported fixed prostheses: randomized controlled clinical trial.

Objectives: To evaluate the trueness of the digital maxillary occlusal records in comparison with the conventional records for the fabrication of complete-arch implant-supported fixed prostheses.

Materials And Methods: This randomized controlled clinical trial followed the recommendations of the CONSORT statement. Twenty participants who used a mandibular interim complete-arch fixed prosthesis and conventional complete maxillary dentures were included in the study.

Targeting bonding protocols to increase the bond between acrylic resin or 3D printed denture bases and prefabricated or 3D printed denture teeth.

Statement Of Problem: The difference in chemical composition between denture base resin and denture teeth requires the development of bonding protocols that increase the union between the materials.

Purpose: The purpose of this in vitro study was to evaluate the impact of different bonding protocols on the bond between heat-polymerized and 3-dimensionally (3D) printed acrylic resin denture bases and acrylic resin prefabricated and 3D printed artificial teeth.

Material And Methods: Four types of artificial teeth were evaluated: prefabricated acrylic resin (VITA MFT) and 3D printed (Cosmos TEMP, PRIZMA 3D Bio Denture, and PrintaX AA Temp) bonded to 20×24-mm cylinders of heat-polymerized (VipiWave) and 3D printed (Cosmos Denture, PRIZMA 3D Bio Denture, and PrintaX BB Base) denture bases.

Impact of using magnifying dental loupes on clinical performance during tooth preparation: A systematic review.

Background: To assess whether using magnification loupes affects tooth preparation working posture performed by undergraduate students and dentistry professionals and whether it influences the quality of the preparation, operator satisfaction and procedure time.

Material And Methods: This review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and registered in the International Prospective Register of Systematic Review (CRD42023482377). Electronic searches were conducted in PubMed/Medline, Cochrane Library, Web of Science, and Scopus databases for relevant articles published up to August 2023.

Digital planning and surveying for a rotational path removable partial denture: a case report.

Digital technology has been applied to the planning and manufacture of removable partial dentures (RPDs), reducing the complexity of RPD treatment as well as the number and duration of clinical and laboratory steps. However, there is a lack of information regarding digital planning and surveying for rotational path RPDs. This article presents a case report of a digital diagnostic wax-up and survey for a rotational path RPD performed with prosthetic design software.

Impact of CAD/CAM Material and Bonding Protocol on the Bond Strength Between Denture Bases and Artificial Teeth: A Systematic Review and Meta-analysis.

Purpose: To identify the most effective protocol for bonding denture bases and artificial teeth made with different computer-aided design and manufacturing (CAD/CAM) materials (milled and 3D-printed) and conventional heat-polymerized resins.

Materials And Methods: This review was performed according to the Preferred Reporting Items for Systematic and Meta-Analysis (PRISMA) criteria and registered in the International Prospective Registry of Systematic Reviews PROSPERO (CRD42021276084). An electronic search was performed independently by two examiners in PubMed/MEDLINE, Cochrane Library, Scopus, Web of Science, ProQuest, and OpenGrey databases for articles published up to and including December 2021.

Factors Associated with Nonadaptation to New Mandibular Complete Dentures: A Scoping Review.

Purpose: To identify and map the scientific evidence regarding factors associated with the nonadaptation of completely edentulous patients to mandibular complete dentures.

Materials And Methods: This scoping review followed the PRISMA-ScR statement for Scoping Reviews and was based on guidelines proposed by Arksey and O'Malley and the Joanna Briggs Institute Manual for Evidence Synthesis. The methodology was registered on the Open Science Framework.

Predicting post-discharge complications in cardiothoracic surgery: A clinical decision support system to optimize remote patient monitoring resources.

Cardiac surgery patients are highly prone to severe complications post-discharge. Close follow-up through remote patient monitoring can help detect adverse outcomes earlier or prevent them, closing the gap between hospital and home care. However, equipment is limited due to economic and human resource constraints.

Does depth divide? Variable genetic connectivity patterns among shallow and mesophotic coral populations across the Gulf of Mexico and western Caribbean.

Despite general declines in coral reef ecosystems in the tropical western Atlantic, some reefs, including mesophotic reefs (30-150 m), are hypothesized to function as coral refugia due to their relative isolation from anthropogenic stressors. Understanding the connectivity dynamics among these putative refugia and more degraded reefs is critical to develop effective management strategies that promote coral metapopulation persistence and recovery. This study presents a geographically broad assessment of shallow (<30 m) and mesophotic (>30 m) connectivity dynamics of the depth-generalist coral species .

Accuracy of models of partially edentulous arches obtained by three-dimensional printing: An study.

Aim: The aim of this study was to evaluate the accuracy of models of partially edentulous arches obtained by three-dimensional (3D) printing.

Settings And Design: This was an in vitro study.

Materials And Methods: Fifteen partially edentulous models were evaluated, using two methods of measuring dimensions: virtual, using the Standard Tessellation Language files of the models and software (control group), and physical, through printing the models and digital caliper (test group).

Use of an Impression Technique to Identify Areas of Super Compression Before Installation of New Complete Dentures: A Randomized Double-Blind Trial.

Purpose: To identify pressure areas using an impression technique and to evaluate whether adjustment of dentures prior to installation can decrease ulcer frequency, reduce the number of adjustments, and improve satisfaction with treatment.

Materials And Methods: A total of 50 complete denture users were selected and randomly divided into two groups. Pressure areas were identified in 25 subjects using the impression technique with fluid silicone, and the denture base in these areas was adjusted before installation.

Bond strength between denture lining material and CAD-CAM denture base resin: A systematic review and meta-analysis.

Statement Of Problem: An effective bond between a denture lining material and the denture base resin is necessary for proper function. Regarding the new technologies for manufacturing denture bases, a systematic search of the literature on this topic is lacking.

Purpose: The purpose of this systematic review and meta-analysis was to evaluate the bond strength between denture lining material and computer-aided design and computer-aided manufacturing (CAD-CAM) denture base resin (milled and 3-dimensionally printed) versus conventional denture base resin.

Virtual facebow techniques: A scoping review.

Statement Of Problem: Although advances in technology continue to improve the acquisition of patient data and the manufacturing of different oral rehabilitations, the method of transferring clinical information to a virtual environment has not yet been consolidated in the literature.

Purpose: The purpose of this scoping review was to map the existing literature on different techniques of transferring information from virtual facebows for oral rehabilitation.

Material And Methods: This scoping review was structured using a 5-step methodology based on guidelines proposed by Arksey and O'Malley: (1) characterization of the research question, (2) identification of relevant studies, (3) selection of studies, (4) mapping of results, and (5) selection, summary and reporting of the data.

Device trueness in passivity and misfit of CAD-CAM frameworks: Conventional versus printed casts.

Statement Of Problem: Obtaining a passive and well-adapted framework is challenging when intraoral scanning edentulous arches with multiple implants. The trueness of the printed casts is unclear.

Purpose: The purpose of this clinical study was to evaluate the trueness of frameworks made from conventional and printed casts regarding clinical passivity and misfit.

Nonadaptation to New Mandibular Complete Dentures: A Survival Analysis and Interpretation of the Time to Adaptation.

Purpose: To determine the average time for patients to adapt to mandibular complete dentures (CDs) and the factors associated with this critical period.

Materials And Methods: In total, 108 completely edentulous patients were rehabilitated using CDs. Adaptation was evaluated based on the following criteria: mastication, comfort, speech, and swallowing with dentures.

Exploring Regularization Methods for Domain Generalization in Accelerometer-Based Human Activity Recognition.

The study of Domain Generalization (DG) has gained considerable momentum in the Machine Learning (ML) field. Human Activity Recognition (HAR) inherently encompasses diverse domains (e.g.