Publications by authors named "Carolyn Nye"

Case Series Summary: Three cats (five stifles) were diagnosed with varying degrees of pelvic limb lameness secondary to medial patellar luxations (MPLs). Lameness did not resolve with medical management in any cat before referral for orthopedic evaluation. All cats underwent semi-cylindrical recession trochleoplasty (SCRT), medial fascial release and lateral imbrication for surgical repair of MPLs.

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Background: Cerebrospinal fluid (CSF) lactate concentrations increase after seizure activity in many human patients independent of the underlying disease process. The effect of seizure activity on CSF lactate concentration in dogs is unknown.

Hypothesis/objectives: Cerebrospinal fluid lactate concentration is unaffected by seizure activity in dogs and is more dependent on the underlying disease process causing the seizures.

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Background: Osseous-associated cervical spondylomyelopathy (OA-CSM) is a complex disorder with limited long-term survival. The longitudinal progression is currently unknown.

Objective: To describe changes on magnetic resonance imaging (MRI) over a 2-year minimum period.

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A 4-year-old female spayed Pomeranian presented for being unable to use its pelvic limbs after a fall. The dog was paraplegic with absent pelvic limb nociception and a Schiff-Sherrington posture. Radiographs and Computed tomography showed a T11-T12 luxation.

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Background: Cerebrospinal fluid (CSF) lactate is frequently used as a biomarker in humans with inflammatory central nervous system (CNS) disorders including bacterial meningitis and autoimmune disorders such as multiple sclerosis.

Hypothesis: Cerebrospinal fluid lactate concentrations are increased in a subset of dogs with inflammatory CNS disorders.

Animals: One hundred two client-owned dogs diagnosed with inflammatory CNS disease.

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Background: Cerebrospinal fluid (CSF) lactate concentration may be a useful diagnostic and prognostic biomarker in dogs. Previous studies have used methods requiring relatively large sample volumes or prolonged storage prior to analysis. An effective method to immediately quantify lactate in smaller CSF volumes would be beneficial.

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Objective: To compare the Lactate Plus handheld monitor to a reference blood gas analyzer for determining plasma lactate concentrations in canine whole blood.

Design: Prospective observational study.

Setting: University teaching hospital.

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